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Coumarin-Based Aldo-Keto Reductase Family 1C (AKR1C) 2 and 3 Inhibitors.
Jonnalagadda SK, Duan L, Dow LF, Boligala GP, Kosmacek E, McCoy K, Oberley-Deegan R, Chhonker YS, Murry DJ, Reynolds CP, Maurer BJ, Penning TM, Trippier PC. Jonnalagadda SK, et al. Among authors: reynolds cp. ChemMedChem. 2024 Nov 4;19(21):e202400081. doi: 10.1002/cmdc.202400081. Epub 2024 Sep 16. ChemMedChem. 2024. PMID: 38976686
Non-synonymous, synonymous, and non-coding nucleotide variants contribute to recurrently altered biological processes during retinoblastoma progression.
Stachelek K, Harutyunyan N, Lee S, Beck A, Kim J, Xu L, Berry JL, Nagiel A, Reynolds CP, Murphree AL, Lee TC, Aparicio JG, Cobrinik D. Stachelek K, et al. Among authors: reynolds cp. Genes Chromosomes Cancer. 2023 May;62(5):275-289. doi: 10.1002/gcc.23120. Epub 2023 Jan 5. Genes Chromosomes Cancer. 2023. PMID: 36550020 Free PMC article.
Reduced ER-mitochondria connectivity promotes neuroblastoma multidrug resistance.
Çoku J, Booth DM, Skoda J, Pedrotty MC, Vogel J, Liu K, Vu A, Carpenter EL, Ye JC, Chen MA, Dunbar P, Scadden E, Yun TD, Nakamaru-Ogiso E, Area-Gomez E, Li Y, Goldsmith KC, Reynolds CP, Hajnoczky G, Hogarty MD. Çoku J, et al. Among authors: reynolds cp. EMBO J. 2022 Apr 19;41(8):e108272. doi: 10.15252/embj.2021108272. Epub 2022 Feb 25. EMBO J. 2022. PMID: 35211994 Free PMC article.
ALT neuroblastoma chemoresistance due to telomere dysfunction-induced ATM activation is reversible with ATM inhibitor AZD0156.
Koneru B, Farooqi A, Nguyen TH, Chen WH, Hindle A, Eslinger C, Makena MR, Burrow TA, Wilson J, Smith A, Pilla Reddy V, Cadogan E, Durant ST, Reynolds CP. Koneru B, et al. Among authors: reynolds cp. Sci Transl Med. 2021 Aug 18;13(607):eabd5750. doi: 10.1126/scitranslmed.abd5750. Sci Transl Med. 2021. PMID: 34408079 Free PMC article.
297 results