Yasukawa H - Search Results

1

SOCS3 is a physiological negative regulator for granulopoiesis and granulocyte colony-stimulating factor receptor signaling.

Kimura A, Kinjyo I, Matsumura Y, Mori H, Mashima R, Harada M, Chien KR, Yasukawa H, Yoshimura A. Kimura A, et al. Among authors: yasukawa h. J Biol Chem. 2004 Feb 20;279(8):6905-10. doi: 10.1074/jbc.C300496200. Epub 2003 Dec 29. J Biol Chem. 2004. PMID: 14699146 Free article.

2

The N-terminal truncated isoform of SOCS3 translated from an alternative initiation AUG codon under stress conditions is stable due to the lack of a major ubiquitination site, Lys-6.

Sasaki A, Inagaki-Ohara K, Yoshida T, Yamanaka A, Sasaki M, Yasukawa H, Koromilas AE, Yoshimura A. Sasaki A, et al. Among authors: yasukawa h. J Biol Chem. 2003 Jan 24;278(4):2432-6. doi: 10.1074/jbc.C200608200. Epub 2002 Nov 28. J Biol Chem. 2003. PMID: 12459551 Free article.

3

Socs3 deficiency in the brain elevates leptin sensitivity and confers resistance to diet-induced obesity.

Mori H, Hanada R, Hanada T, Aki D, Mashima R, Nishinakamura H, Torisu T, Chien KR, Yasukawa H, Yoshimura A. Mori H, et al. Among authors: yasukawa h. Nat Med. 2004 Jul;10(7):739-43. doi: 10.1038/nm1071. Epub 2004 Jun 20. Nat Med. 2004. PMID: 15208705

4

A mutant form of JAB/SOCS1 augments the cytokine-induced JAK/STAT pathway by accelerating degradation of wild-type JAB/CIS family proteins through the SOCS-box.

Hanada T, Yoshida T, Kinjyo I, Minoguchi S, Yasukawa H, Kato S, Mimata H, Nomura Y, Seki Y, Kubo M, Yoshimura A. Hanada T, et al. Among authors: yasukawa h. J Biol Chem. 2001 Nov 2;276(44):40746-54. doi: 10.1074/jbc.M106139200. Epub 2001 Aug 24. J Biol Chem. 2001. PMID: 11522790 Free article.

5

IL-6 induces an anti-inflammatory response in the absence of SOCS3 in macrophages.

Yasukawa H, Ohishi M, Mori H, Murakami M, Chinen T, Aki D, Hanada T, Takeda K, Akira S, Hoshijima M, Hirano T, Chien KR, Yoshimura A. Yasukawa H, et al. Nat Immunol. 2003 Jun;4(6):551-6. doi: 10.1038/ni938. Epub 2003 May 18. Nat Immunol. 2003. PMID: 12754507

6

Negative regulation of cytokine signaling pathways.

Yasukawa H, Sasaki A, Yoshimura A. Yasukawa H, et al. Annu Rev Immunol. 2000;18:143-64. doi: 10.1146/annurev.immunol.18.1.143. Annu Rev Immunol. 2000. PMID: 10837055 Review.

7

CIS3/SOCS-3 suppresses erythropoietin (EPO) signaling by binding the EPO receptor and JAK2.

Sasaki A, Yasukawa H, Shouda T, Kitamura T, Dikic I, Yoshimura A. Sasaki A, et al. Among authors: yasukawa h. J Biol Chem. 2000 Sep 22;275(38):29338-47. doi: 10.1074/jbc.M003456200. J Biol Chem. 2000. PMID: 10882725 Free article.

8

Suppressors of cytokine signaling (SOCS) proteins and JAK/STAT pathways: regulation of T-cell inflammation by SOCS1 and SOCS3.

Tamiya T, Kashiwagi I, Takahashi R, Yasukawa H, Yoshimura A. Tamiya T, et al. Among authors: yasukawa h. Arterioscler Thromb Vasc Biol. 2011 May;31(5):980-5. doi: 10.1161/ATVBAHA.110.207464. Arterioscler Thromb Vasc Biol. 2011. PMID: 21508344 Review.

9

The suppressor of cytokine signaling-1 (SOCS1) is a novel therapeutic target for enterovirus-induced cardiac injury.

Yasukawa H, Yajima T, Duplain H, Iwatate M, Kido M, Hoshijima M, Weitzman MD, Nakamura T, Woodard S, Xiong D, Yoshimura A, Chien KR, Knowlton KU. Yasukawa H, et al. J Clin Invest. 2003 Feb;111(4):469-78. doi: 10.1172/JCI16491. J Clin Invest. 2003. PMID: 12588885 Free PMC article.

10

Loss of suppressor of cytokine signaling 1 in helper T cells leads to defective Th17 differentiation by enhancing antagonistic effects of IFN-gamma on STAT3 and Smads.

Tanaka K, Ichiyama K, Hashimoto M, Yoshida H, Takimoto T, Takaesu G, Torisu T, Hanada T, Yasukawa H, Fukuyama S, Inoue H, Nakanishi Y, Kobayashi T, Yoshimura A. Tanaka K, et al. Among authors: yasukawa h. J Immunol. 2008 Mar 15;180(6):3746-56. doi: 10.4049/jimmunol.180.6.3746. J Immunol. 2008. PMID: 18322180

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