Roe SM - Search Results

1

GSK-3-selective inhibitors derived from Tyrian purple indirubins.

Meijer L, Skaltsounis AL, Magiatis P, Polychronopoulos P, Knockaert M, Leost M, Ryan XP, Vonica CA, Brivanlou A, Dajani R, Crovace C, Tarricone C, Musacchio A, Roe SM, Pearl L, Greengard P. Meijer L, et al. Among authors: roe sm. Chem Biol. 2003 Dec;10(12):1255-66. doi: 10.1016/j.chembiol.2003.11.010. Chem Biol. 2003. PMID: 14700633

2

Structural basis for the synthesis of indirubins as potent and selective inhibitors of glycogen synthase kinase-3 and cyclin-dependent kinases.

Polychronopoulos P, Magiatis P, Skaltsounis AL, Myrianthopoulos V, Mikros E, Tarricone A, Musacchio A, Roe SM, Pearl L, Leost M, Greengard P, Meijer L. Polychronopoulos P, et al. Among authors: roe sm. J Med Chem. 2004 Feb 12;47(4):935-46. doi: 10.1021/jm031016d. J Med Chem. 2004. PMID: 14761195

3

Structural basis for recruitment of glycogen synthase kinase 3beta to the axin-APC scaffold complex.

Dajani R, Fraser E, Roe SM, Yeo M, Good VM, Thompson V, Dale TC, Pearl LH. Dajani R, et al. Among authors: roe sm. EMBO J. 2003 Feb 3;22(3):494-501. doi: 10.1093/emboj/cdg068. EMBO J. 2003. PMID: 12554650 Free PMC article.

4

Crystal structure of glycogen synthase kinase 3 beta: structural basis for phosphate-primed substrate specificity and autoinhibition.

Dajani R, Fraser E, Roe SM, Young N, Good V, Dale TC, Pearl LH. Dajani R, et al. Among authors: roe sm. Cell. 2001 Jun 15;105(6):721-32. doi: 10.1016/s0092-8674(01)00374-9. Cell. 2001. PMID: 11440715 Free article.

5

Inhibition of Hsp90 with synthetic macrolactones: synthesis and structural and biological evaluation of ring and conformational analogs of radicicol.

Proisy N, Sharp SY, Boxall K, Connelly S, Roe SM, Prodromou C, Slawin AM, Pearl LH, Workman P, Moody CJ. Proisy N, et al. Among authors: roe sm. Chem Biol. 2006 Nov;13(11):1203-15. doi: 10.1016/j.chembiol.2006.09.015. Chem Biol. 2006. PMID: 17114002

6

Crystal structure of the CCTgamma apical domain: implications for substrate binding to the eukaryotic cytosolic chaperonin.

Pappenberger G, Wilsher JA, Roe SM, Counsell DJ, Willison KR, Pearl LH. Pappenberger G, et al. Among authors: roe sm. J Mol Biol. 2002 May 17;318(5):1367-79. doi: 10.1016/s0022-2836(02)00190-0. J Mol Biol. 2002. PMID: 12083524

7

Structural basis for recruitment of translesion DNA polymerase Pol IV/DinB to the beta-clamp.

Bunting KA, Roe SM, Pearl LH. Bunting KA, et al. Among authors: roe sm. EMBO J. 2003 Nov 3;22(21):5883-92. doi: 10.1093/emboj/cdg568. EMBO J. 2003. PMID: 14592985 Free PMC article.

8

Insights into histone code syntax from structural and biochemical studies of CARM1 methyltransferase.

Yue WW, Hassler M, Roe SM, Thompson-Vale V, Pearl LH. Yue WW, et al. Among authors: roe sm. EMBO J. 2007 Oct 17;26(20):4402-12. doi: 10.1038/sj.emboj.7601856. Epub 2007 Sep 20. EMBO J. 2007. PMID: 17882261 Free PMC article.

9

Crystal structure of the catalytic fragment of murine poly(ADP-ribose) polymerase-2.

Oliver AW, Amé JC, Roe SM, Good V, de Murcia G, Pearl LH. Oliver AW, et al. Among authors: roe sm. Nucleic Acids Res. 2004 Jan 22;32(2):456-64. doi: 10.1093/nar/gkh215. Print 2004. Nucleic Acids Res. 2004. PMID: 14739238 Free PMC article.

10

Crystal structure of alanine:glyoxylate aminotransferase and the relationship between genotype and enzymatic phenotype in primary hyperoxaluria type 1.

Zhang X, Roe SM, Hou Y, Bartlam M, Rao Z, Pearl LH, Danpure CJ. Zhang X, et al. Among authors: roe sm. J Mol Biol. 2003 Aug 15;331(3):643-52. doi: 10.1016/s0022-2836(03)00791-5. J Mol Biol. 2003. PMID: 12899834

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