Heinrich T - Search Results

1

Palladium-catalyzed carbonylation of haloindoles: no need for protecting groups.

Kumar K, Zapf A, Michalik D, Tillack A, Heinrich T, Böttcher H, Arlt M, Beller M. Kumar K, et al. Among authors: heinrich t. Org Lett. 2004 Jan 8;6(1):7-10. doi: 10.1021/ol035988r. Org Lett. 2004. PMID: 14703337

2

Biologically active compounds through catalysis: efficient synthesis of N-(heteroarylcarbonyl)-N'-(arylalkyl)piperazines.

Kumar K, Michalik D, Garcia Castro I, Tillack A, Zapf A, Arlt M, Heinrich T, Böttcher H, Beller M. Kumar K, et al. Among authors: heinrich t. Chemistry. 2004 Feb 6;10(3):746-57. doi: 10.1002/chem.200305327. Chemistry. 2004. PMID: 14767940

3

A new synthesis of indole 5-carboxylic acids and 6-hydroxy-indole-5-carboxylic acids in the preparation of an o-hydroxylated metabolite of vilazodone.

Heinrich T, Böttcher H. Heinrich T, et al. Bioorg Med Chem Lett. 2004 May 17;14(10):2681-4. doi: 10.1016/j.bmcl.2004.01.110. Bioorg Med Chem Lett. 2004. PMID: 15109678

4

Syntheses of novel 2,3-diaryl-substituted 5-cyano-4-azaindoles exhibiting c-Met inhibition activity.

Koolman H, Heinrich T, Böttcher H, Rautenberg W, Reggelin M. Koolman H, et al. Among authors: heinrich t. Bioorg Med Chem Lett. 2009 Apr 1;19(7):1879-82. doi: 10.1016/j.bmcl.2009.02.069. Epub 2009 Feb 21. Bioorg Med Chem Lett. 2009. PMID: 19269177

5

Allosteric IGF-1R Inhibitors.

Heinrich T, Grädler U, Böttcher H, Blaukat A, Shutes A. Heinrich T, et al. ACS Med Chem Lett. 2010 May 18;1(5):199-203. doi: 10.1021/ml100044h. eCollection 2010 Aug 12. ACS Med Chem Lett. 2010. PMID: 24900194 Free PMC article.

6

Indolebutylamines as selective 5-HT(1A) agonists.

Heinrich T, Böttcher H, Bartoszyk GD, Greiner HE, Seyfried CA, Van Amsterdam C. Heinrich T, et al. J Med Chem. 2004 Sep 9;47(19):4677-83. doi: 10.1021/jm040792y. J Med Chem. 2004. PMID: 15341483

7

Dual 5-HT1A agonists and 5-HT re-uptake inhibitors by combination of indole-butyl-amine and chromenonyl-piperazine structural elements in a single molecular entity.

Heinrich T, Böttcher H, Schiemann K, Hölzemann G, Schwarz M, Bartoszyk GD, van Amsterdam C, Greiner HE, Seyfried CA. Heinrich T, et al. Bioorg Med Chem. 2004 Sep 15;12(18):4843-52. doi: 10.1016/j.bmc.2004.07.014. Bioorg Med Chem. 2004. PMID: 15336263

8

1-(1-phenethylpiperidin-4-yl)-1-phenylethanols as potent and highly selective 5-HT2A antagonists.

Heinrich T, Böttcher H, Prücher H, Gottschlich R, Ackermann KA, van Amsterdam C. Heinrich T, et al. ChemMedChem. 2006 Feb;1(2):245-55. doi: 10.1002/cmdc.200500023. ChemMedChem. 2006. PMID: 16892357

9

Synthesis and structure--activity relationship in a class of indolebutylpiperazines as dual 5-HT(1A) receptor agonists and serotonin reuptake inhibitors.

Heinrich T, Böttcher H, Gericke R, Bartoszyk GD, Anzali S, Seyfried CA, Greiner HE, Van Amsterdam C. Heinrich T, et al. J Med Chem. 2004 Sep 9;47(19):4684-92. doi: 10.1021/jm040793q. J Med Chem. 2004. PMID: 15341484

10

Asymmetric synthesis of highly substituted azapolycyclic compounds via 2-alkenyl sulfoximines: potential scaffolds for peptide mimetics.

Reggelin M, Junker B, Heinrich T, Slavik S, Bühle P. Reggelin M, et al. Among authors: heinrich t. J Am Chem Soc. 2006 Mar 29;128(12):4023-34. doi: 10.1021/ja057012a. J Am Chem Soc. 2006. PMID: 16551111

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