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Farming on the edge: farmer attitudes to bovine tuberculosis in newly endemic areas.
Enticott G, Maye D, Carmody P, Naylor R, Ward K, Hinchliffe S, Wint W, Alexander N, Elgin R, Ashton A, Upton P, Nicholson R, Goodchild T, Brunton L, Broughan J. Enticott G, et al. Among authors: goodchild t. Vet Rec. 2015 Oct 31;177(17):439. doi: 10.1136/vr.103187. Epub 2015 Oct 22. Vet Rec. 2015. PMID: 26494770
Dysregulation of Nitrosylation Dynamics Promotes Nitrosative Stress and Contributes to Cardiometabolic Heart Failure with Preserved Ejection Fraction.
Li Z, LaPenna KB, Gehred ND, Yu X, Tang WHW, Doiron JE, Xia H, Chen J, Driver IH, Sachse FB, Muraoka N, Katsouda A, Zampas P, Haydel AG, Quiriarte H, Zagouras A, Wilcox J, Gromova T, Shah SJ, Goodchild TT, Allerton TD, Jensen MB, Papapetropoulos A, Sharp TE, Vondriska TM, Lefer DJ. Li Z, et al. Among authors: goodchild tt. bioRxiv [Preprint]. 2024 Dec 23:2024.12.20.629549. doi: 10.1101/2024.12.20.629549. bioRxiv. 2024. PMID: 39763741 Free PMC article. Preprint.
Integrated systems biology identifies disruptions in mitochondrial function and metabolism as key contributors to heart failure with preserved ejection fraction (HFpEF).
Gibb AA, LaPenna K, Gaspar RB, Latchman NR, Tan Y, Choya-Foces C, Doiron JE, Li Z, Xia H, Lazaropoulos MP, Conwell M, Sharp TE 3rd, Goodchild TT, Lefer DJ, Elrod JW. Gibb AA, et al. Among authors: goodchild tt. bioRxiv [Preprint]. 2024 Oct 25:2024.10.25.619450. doi: 10.1101/2024.10.25.619450. bioRxiv. 2024. PMID: 39484400 Free PMC article. Preprint.
Reduced Hydrogen Sulfide Bioavailability Contributes to Cardiometabolic Heart Failure with Preserved Ejection Fraction.
Doiron JE, Elbatreek MH, Xia H, Yu X, Wilson Tang WH, LaPenna KB, Sharp TE, Goodchild TT, Xian M, Xu S, Quiriarte H, Allerton TD, Zagouras A, Wilcox J, Shah SJ, Pfeilschifter J, Beck KF, Li Z, Lefer DJ. Doiron JE, et al. Among authors: goodchild tt. bioRxiv [Preprint]. 2024 Sep 19:2024.09.16.613349. doi: 10.1101/2024.09.16.613349. bioRxiv. 2024. PMID: 39345440 Free PMC article. Preprint.
Adjunctive therapy with an oral H2S donor provides additional therapeutic benefit beyond SGLT2 inhibition in cardiometabolic heart failure with preserved ejection fraction.
Doiron JE, Xia H, Yu X, Nevins AR, LaPenna KB, Sharp TE 3rd, Goodchild TT, Allerton TD, Elgazzaz M, Lazartigues E, Shah SJ, Li Z, Lefer DJ. Doiron JE, et al. Among authors: goodchild tt. Br J Pharmacol. 2024 Nov;181(21):4294-4310. doi: 10.1111/bph.16493. Epub 2024 Jul 9. Br J Pharmacol. 2024. PMID: 38982742
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