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IFNalpha-stimulated neutrophils and monocytes release a soluble form of TNF-related apoptosis-inducing ligand (TRAIL/Apo-2 ligand) displaying apoptotic activity on leukemic cells.
Tecchio C, Huber V, Scapini P, Calzetti F, Margotto D, Todeschini G, Pilla L, Martinelli G, Pizzolo G, Rivoltini L, Cassatella MA. Tecchio C, et al. Among authors: margotto d. Blood. 2004 May 15;103(10):3837-44. doi: 10.1182/blood-2003-08-2806. Epub 2004 Jan 15. Blood. 2004. PMID: 14726404 Free article.
Interferon-activated neutrophils store a TNF-related apoptosis-inducing ligand (TRAIL/Apo-2 ligand) intracellular pool that is readily mobilizable following exposure to proinflammatory mediators.
Cassatella MA, Huber V, Calzetti F, Margotto D, Tamassia N, Peri G, Mantovani A, Rivoltini L, Tecchio C. Cassatella MA, et al. Among authors: margotto d. J Leukoc Biol. 2006 Jan;79(1):123-32. doi: 10.1189/jlb.0805431. Epub 2005 Oct 21. J Leukoc Biol. 2006. PMID: 16244105
Anti-inflammatory actions of St. John's wort: inhibition of human inducible nitric-oxide synthase expression by down-regulating signal transducer and activator of transcription-1alpha (STAT-1alpha) activation.
Tedeschi E, Menegazzi M, Margotto D, Suzuki H, Förstermann U, Kleinert H. Tedeschi E, et al. Among authors: margotto d. J Pharmacol Exp Ther. 2003 Oct;307(1):254-61. doi: 10.1124/jpet.103.054460. Epub 2003 Sep 3. J Pharmacol Exp Ther. 2003. PMID: 12954801