Kucab JE - Search Results

1

Expression of the insulin-like growth factor I receptor and urokinase plasminogen activator in breast cancer is associated with poor survival: potential for intervention with 17-allylamino geldanamycin.

Nielsen TO, Andrews HN, Cheang M, Kucab JE, Hsu FD, Ragaz J, Gilks CB, Makretsov N, Bajdik CD, Brookes C, Neckers LM, Evdokimova V, Huntsman DG, Dunn SE. Nielsen TO, et al. Among authors: kucab je. Cancer Res. 2004 Jan 1;64(1):286-91. doi: 10.1158/0008-5472.can-03-1242. Cancer Res. 2004. PMID: 14729636

2

Celecoxib analogues disrupt Akt signaling, which is commonly activated in primary breast tumours.

Kucab JE, Lee C, Chen CS, Zhu J, Gilks CB, Cheang M, Huntsman D, Yorida E, Emerman J, Pollak M, Dunn SE. Kucab JE, et al. Breast Cancer Res. 2005;7(5):R796-807. doi: 10.1186/bcr1294. Epub 2005 Aug 1. Breast Cancer Res. 2005. PMID: 16168126 Free PMC article.

3

Celecoxib inhibits urokinase-type plasminogen activator (uPA) production in MDA-MB-231 breast cancer cells.

Andrews HN, Habibi G, Kucab JE, Dunn SE. Andrews HN, et al. Among authors: kucab je. Breast Cancer Res Treat. 2005 Nov;94(1):47-52. doi: 10.1007/s10549-005-6941-5. Breast Cancer Res Treat. 2005. PMID: 16172791

4

Preferential dependence of breast cancer cells versus normal cells on integrin-linked kinase for protein kinase B/Akt activation and cell survival.

Troussard AA, McDonald PC, Wederell ED, Mawji NM, Filipenko NR, Gelmon KA, Kucab JE, Dunn SE, Emerman JT, Bally MB, Dedhar S. Troussard AA, et al. Among authors: kucab je. Cancer Res. 2006 Jan 1;66(1):393-403. doi: 10.1158/0008-5472.CAN-05-2304. Cancer Res. 2006. PMID: 16397254 Free article.

5

Role of IGF-1R in mediating breast cancer invasion and metastasis.

Kucab JE, Dunn SE. Kucab JE, et al. Breast Dis. 2003;17:41-7. doi: 10.3233/bd-2003-17105. Breast Dis. 2003. PMID: 15687676

6

Akt phosphorylates the Y-box binding protein 1 at Ser102 located in the cold shock domain and affects the anchorage-independent growth of breast cancer cells.

Sutherland BW, Kucab J, Wu J, Lee C, Cheang MC, Yorida E, Turbin D, Dedhar S, Nelson C, Pollak M, Leighton Grimes H, Miller K, Badve S, Huntsman D, Blake-Gilks C, Chen M, Pallen CJ, Dunn SE. Sutherland BW, et al. Oncogene. 2005 Jun 16;24(26):4281-92. doi: 10.1038/sj.onc.1208590. Oncogene. 2005. PMID: 15806160

7

Insulin-like growth factor-1 inscribes a gene expression profile for angiogenic factors and cancer progression in breast epithelial cells.

Oh JS, Kucab JE, Bushel PR, Martin K, Bennett L, Collins J, DiAugustine RP, Barrett JC, Afshari CA, Dunn SE. Oh JS, et al. Among authors: kucab je. Neoplasia. 2002 May-Jun;4(3):204-17. doi: 10.1038/sj.neo.7900229. Neoplasia. 2002. PMID: 11988840 Free PMC article.

8

Nutlin-3a selects for cells harbouring TP53 mutations.

Kucab JE, Hollstein M, Arlt VM, Phillips DH. Kucab JE, et al. Int J Cancer. 2017 Feb 15;140(4):877-887. doi: 10.1002/ijc.30504. Epub 2016 Nov 22. Int J Cancer. 2017. PMID: 27813088 Free PMC article.

9

TP53 mutations induced by BPDE in Xpa-WT and Xpa-Null human TP53 knock-in (Hupki) mouse embryo fibroblasts.

Kucab JE, van Steeg H, Luijten M, Schmeiser HH, White PA, Phillips DH, Arlt VM. Kucab JE, et al. Mutat Res. 2015 Mar;773:48-62. doi: 10.1016/j.mrfmmm.2015.01.013. Epub 2015 Jan 30. Mutat Res. 2015. PMID: 25847421 Free PMC article.

10

Comparison of the metabolic activation of environmental carcinogens in mouse embryonic stem cells and mouse embryonic fibroblasts.

Krais AM, Mühlbauer KR, Kucab JE, Chinbuah H, Cornelius MG, Wei QX, Hollstein M, Phillips DH, Arlt VM, Schmeiser HH. Krais AM, et al. Among authors: kucab je. Toxicol In Vitro. 2015 Feb;29(1):34-43. doi: 10.1016/j.tiv.2014.09.004. Epub 2014 Sep 16. Toxicol In Vitro. 2015. PMID: 25230394 Free PMC article.

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