Heald SL - Search Results

1

Omega-carboxypyridyl substituted ureas as Raf kinase inhibitors: SAR of the amide substituent.

Khire UR, Bankston D, Barbosa J, Brittelli DR, Caringal Y, Carlson R, Dumas J, Gane T, Heald SL, Hibner B, Johnson JS, Katz ME, Kennure N, Kingery-Wood J, Lee W, Liu XG, Lowinger TB, McAlexander I, Monahan MK, Natero R, Renick J, Riedl B, Rong H, Sibley RN, Smith RA, Wolanin D. Khire UR, et al. Among authors: heald sl. Bioorg Med Chem Lett. 2004 Feb 9;14(3):783-6. doi: 10.1016/j.bmcl.2003.11.041. Bioorg Med Chem Lett. 2004. PMID: 14741289

2

Simple selection criteria for drug-like chemical matter.

Muegge I, Heald SL, Brittelli D. Muegge I, et al. Among authors: heald sl. J Med Chem. 2001 Jun 7;44(12):1841-6. doi: 10.1021/jm015507e. J Med Chem. 2001. PMID: 11384230

3

Indanylacetic acids as PPAR-delta activator insulin sensitizers.

Wickens P, Zhang C, Ma X, Zhao Q, Amatruda J, Bullock W, Burns M, Cantin LD, Chuang CY, Claus T, Dai M, Dela Cruz F, Dickson D, Ehrgott FJ, Fan D, Heald S, Hentemann M, Iwuagwu CI, Johnson JS, Kumarasinghe E, Ladner D, Lavoie R, Liang S, Livingston JN, Lowe D, Magnuson S, Mannelly G, Mugge I, Ogutu H, Pleasic-Williams S, Schoenleber RW, Shapiro J, Shelekhin T, Sweet L, Town C, Tsutsumi M. Wickens P, et al. Bioorg Med Chem Lett. 2007 Aug 1;17(15):4369-73. doi: 10.1016/j.bmcl.2007.03.057. Epub 2007 Mar 23. Bioorg Med Chem Lett. 2007. PMID: 17601734

4

Isolation, identification and synthesis of an endogenous arachidonic amide that inhibits calcium channel antagonist 1,4-dihydropyridine binding.

Johnson DE, Heald SL, Dally RD, Janis RA. Johnson DE, et al. Among authors: heald sl. Prostaglandins Leukot Essent Fatty Acids. 1993 Jun;48(6):429-37. doi: 10.1016/0952-3278(93)90048-2. Prostaglandins Leukot Essent Fatty Acids. 1993. PMID: 8341720

5

Structural elements pertinent to the interaction of cyclosporin A with its specific receptor protein, cyclophilin.

Hsu VL, Heald SL, Harding MW, Handschumacher RE, Armitage IM. Hsu VL, et al. Among authors: heald sl. Biochem Pharmacol. 1990 Jul 1;40(1):131-40. doi: 10.1016/0006-2952(90)90188-q. Biochem Pharmacol. 1990. PMID: 2196880 Free article.

6

Performance of a neural-network-based determination of amino acid class and secondary structure from 1H-15N NMR data.

Huang K, Andrec M, Heald S, Blake P, Prestegard JH. Huang K, et al. J Biomol NMR. 1997 Jul;10(1):45-52. doi: 10.1023/a:1018340603528. J Biomol NMR. 1997. PMID: 9335115

7

Sequential NMR resonance assignment and structure determination of the Kunitz-type inhibitor domain of the Alzheimer's beta-amyloid precursor protein.

Heald SL, Tilton RF Jr, Hammond LJ, Lee A, Bayney RM, Kamarck ME, Ramabhadran TV, Dreyer RN, Davis G, Unterbeck A, et al. Heald SL, et al. Biochemistry. 1991 Oct 29;30(43):10467-78. doi: 10.1021/bi00107a015. Biochemistry. 1991. PMID: 1718421

8

1H NMR studies on bovine cyclophilin: preliminary structural characterization of its complex with cyclosporin A.

Heald SL, Harding MW, Handschumacher RE, Armitage IM. Heald SL, et al. Biochemistry. 1990 May 8;29(18):4466-78. doi: 10.1021/bi00470a029. Biochemistry. 1990. PMID: 2190633

9

Synthesis of iodine-125 labeled (+/-)-15-(4-azidobenzyl)carazolol: a potent beta-adrenergic photoaffinity probe.

Heald SL, Jeffs PW, Lavin TN, Nambi P, Lefkowitz RJ, Caron MG. Heald SL, et al. J Med Chem. 1983 Jun;26(6):832-8. doi: 10.1021/jm00360a009. J Med Chem. 1983. PMID: 6304313

10

Actinoidins A and A2: structure determination using 2D NMR methods.

Heald SL, Mueller L, Jeffs PW. Heald SL, et al. J Antibiot (Tokyo). 1987 May;40(5):630-45. doi: 10.7164/antibiotics.40.630. J Antibiot (Tokyo). 1987. PMID: 3610822 Free article.

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