Stearns RA - Search Results

1

Identification of a hydroxylamine glucuronide metabolite of an oral hypoglycemic agent.

Miller RR, Doss GA, Stearns RA. Miller RR, et al. Among authors: stearns ra. Drug Metab Dispos. 2004 Feb;32(2):178-85. doi: 10.1124/dmd.32.2.178. Drug Metab Dispos. 2004. PMID: 14744939

2

Metabolism of a thiazole benzenesulfonamide derivative, a potent and elective agonist of the human beta3-adrenergic receptor, in rats: identification of a novel isethionic acid conjugate.

Tang W, Stearns RA, Miller RR, Ngui JS, Mathvink RJ, Weber AE, Kwei GY, Strauss JR, Keohane CA, Doss GA, Chiu SH, Baillie TA. Tang W, et al. Among authors: stearns ra. Drug Metab Dispos. 2002 Jul;30(7):778-87. doi: 10.1124/dmd.30.7.778. Drug Metab Dispos. 2002. PMID: 12065436

3

A novel P450-catalyzed transformation of the 2,2,6,6-tetramethyl piperidine moiety to a 2,2-dimethyl pyrrolidine in human liver microsomes: characterization by high resolution quadrupole-time-of-flight mass spectrometry and 1H-NMR.

Yin W, Doss GA, Stearns RA, Chaudhary AG, Hop CE, Franklin RB, Kumar S. Yin W, et al. Among authors: stearns ra. Drug Metab Dispos. 2003 Feb;31(2):215-23. doi: 10.1124/dmd.31.2.215. Drug Metab Dispos. 2003. PMID: 12527703

4

N-acetylation of the glutamate residue of intact glutathione conjugates in rats: a novel pathway for the metabolic processing of thiol adducts of xenobiotics.

Yin W, Doss GA, Stearns RA, Kumar S. Yin W, et al. Among authors: stearns ra. Drug Metab Dispos. 2004 Jan;32(1):43-8. doi: 10.1124/dmd.32.1.43. Drug Metab Dispos. 2004. PMID: 14709619

5

Metabolic activation of fluoropyrrolidine dipeptidyl peptidase-IV inhibitors by rat liver microsomes.

Xu S, Zhu B, Teffera Y, Pan DE, Caldwell CG, Doss G, Stearns RA, Evans DC, Beconi MG. Xu S, et al. Among authors: stearns ra. Drug Metab Dispos. 2005 Jan;33(1):121-30. doi: 10.1124/dmd.104.001842. Epub 2004 Oct 14. Drug Metab Dispos. 2005. PMID: 15486074

6

Evidence for the bioactivation of zomepirac and tolmetin by an oxidative pathway: identification of glutathione adducts in vitro in human liver microsomes and in vivo in rats.

Chen Q, Doss GA, Tung EC, Liu W, Tang YS, Braun MP, Didolkar V, Strauss JR, Wang RW, Stearns RA, Evans DC, Baillie TA, Tang W. Chen Q, et al. Among authors: stearns ra. Drug Metab Dispos. 2006 Jan;34(1):145-51. doi: 10.1124/dmd.105.004341. Epub 2005 Oct 26. Drug Metab Dispos. 2006. PMID: 16251255

7

In vitro metabolic activation of lumiracoxib in rat and human liver preparations.

Li Y, Slatter JG, Zhang Z, Li Y, Doss GA, Braun MP, Stearns RA, Dean DC, Baillie TA, Tang W. Li Y, et al. Among authors: stearns ra. Drug Metab Dispos. 2008 Feb;36(2):469-73. doi: 10.1124/dmd.107.019018. Epub 2007 Nov 12. Drug Metab Dispos. 2008. PMID: 17998295

8

The metabolism of DuP 753, a nonpeptide angiotensin II receptor antagonist, by rat, monkey, and human liver slices.

Stearns RA, Miller RR, Doss GA, Chakravarty PK, Rosegay A, Gatto GJ, Chiu SH. Stearns RA, et al. Drug Metab Dispos. 1992 Mar-Apr;20(2):281-7. Drug Metab Dispos. 1992. PMID: 1352222

9

Synthesis and identification of a novel tetrazole metabolite of the angiotensin II receptor antagonist DuP 753.

Stearns RA, Doss GA, Miller RR, Chiu SH. Stearns RA, et al. Drug Metab Dispos. 1991 Nov-Dec;19(6):1160-2. Drug Metab Dispos. 1991. PMID: 1687025 No abstract available.

10

Metabolites of L-735,524, a potent HIV-1 protease inhibitor, in human urine.

Balani SK, Arison BH, Mathai L, Kauffman LR, Miller RR, Stearns RA, Chen IW, Lin JH. Balani SK, et al. Among authors: stearns ra. Drug Metab Dispos. 1995 Feb;23(2):266-70. Drug Metab Dispos. 1995. PMID: 7736923 Clinical Trial.

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