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Donor APCs are required for maximal GVHD but not for GVL.
Matte CC, Liu J, Cormier J, Anderson BE, Athanasiadis I, Jain D, McNiff J, Shlomchik WD. Matte CC, et al. Nat Med. 2004 Sep;10(9):987-92. doi: 10.1038/nm1089. Epub 2004 Aug 1. Nat Med. 2004. PMID: 15286785 Free article.
Stromal cells control the epithelial residence of DCs and memory T cells by regulated activation of TGF-β.
Mohammed J, Beura LK, Bobr A, Astry B, Chicoine B, Kashem SW, Welty NE, Igyártó BZ, Wijeyesinghe S, Thompson EA, Matte C, Bartholin L, Kaplan A, Sheppard D, Bridges AG, Shlomchik WD, Masopust D, Kaplan DH. Mohammed J, et al. Nat Immunol. 2016 Apr;17(4):414-21. doi: 10.1038/ni.3396. Epub 2016 Feb 22. Nat Immunol. 2016. PMID: 26901152 Free PMC article.