Helmlinger D - Search Results

1

Disease progression despite early loss of polyglutamine protein expression in SCA7 mouse model.

Helmlinger D, Abou-Sleymane G, Yvert G, Rousseau S, Weber C, Trottier Y, Mandel JL, Devys D. Helmlinger D, et al. J Neurosci. 2004 Feb 25;24(8):1881-7. doi: 10.1523/JNEUROSCI.4407-03.2004. J Neurosci. 2004. PMID: 14985428 Free PMC article.

2

SCA7 mouse models show selective stabilization of mutant ataxin-7 and similar cellular responses in different neuronal cell types.

Yvert G, Lindenberg KS, Devys D, Helmlinger D, Landwehrmeyer GB, Mandel JL. Yvert G, et al. Among authors: helmlinger d. Hum Mol Genet. 2001 Aug 1;10(16):1679-92. doi: 10.1093/hmg/10.16.1679. Hum Mol Genet. 2001. PMID: 11487572

3

Progressive retinal degeneration and dysfunction in R6 Huntington's disease mice.

Helmlinger D, Yvert G, Picaud S, Merienne K, Sahel J, Mandel JL, Devys D. Helmlinger D, et al. Hum Mol Genet. 2002 Dec 15;11(26):3351-9. doi: 10.1093/hmg/11.26.3351. Hum Mol Genet. 2002. PMID: 12471061

4

Polyglutamine expansion induces a protein-damaging stress connecting heat shock protein 70 to the JNK pathway.

Merienne K, Helmlinger D, Perkin GR, Devys D, Trottier Y. Merienne K, et al. Among authors: helmlinger d. J Biol Chem. 2003 May 9;278(19):16957-67. doi: 10.1074/jbc.M212049200. Epub 2003 Feb 21. J Biol Chem. 2003. PMID: 12598532 Free article.

5

Ataxin-7 is a subunit of GCN5 histone acetyltransferase-containing complexes.

Helmlinger D, Hardy S, Sasorith S, Klein F, Robert F, Weber C, Miguet L, Potier N, Van-Dorsselaer A, Wurtz JM, Mandel JL, Tora L, Devys D. Helmlinger D, et al. Hum Mol Genet. 2004 Jun 15;13(12):1257-65. doi: 10.1093/hmg/ddh139. Epub 2004 Apr 28. Hum Mol Genet. 2004. PMID: 15115762

6

Hsp70 and Hsp40 chaperones do not modulate retinal phenotype in SCA7 mice.

Helmlinger D, Bonnet J, Mandel JL, Trottier Y, Devys D. Helmlinger D, et al. J Biol Chem. 2004 Dec 31;279(53):55969-77. doi: 10.1074/jbc.M409062200. Epub 2004 Oct 19. J Biol Chem. 2004. PMID: 15494410 Free article.

7

Polyglutamine expansion causes neurodegeneration by altering the neuronal differentiation program.

Abou-Sleymane G, Chalmel F, Helmlinger D, Lardenois A, Thibault C, Weber C, Mérienne K, Mandel JL, Poch O, Devys D, Trottier Y. Abou-Sleymane G, et al. Among authors: helmlinger d. Hum Mol Genet. 2006 Mar 1;15(5):691-703. doi: 10.1093/hmg/ddi483. Epub 2006 Jan 24. Hum Mol Genet. 2006. PMID: 16434483

8

Glutamine-expanded ataxin-7 alters TFTC/STAGA recruitment and chromatin structure leading to photoreceptor dysfunction.

Helmlinger D, Hardy S, Abou-Sleymane G, Eberlin A, Bowman AB, Gansmüller A, Picaud S, Zoghbi HY, Trottier Y, Tora L, Devys D. Helmlinger D, et al. PLoS Biol. 2006 Mar;4(3):e67. doi: 10.1371/journal.pbio.0040067. Epub 2006 Feb 28. PLoS Biol. 2006. PMID: 16494529 Free PMC article.

9

Both normal and polyglutamine- expanded ataxin-7 are components of TFTC-type GCN5 histone acetyltransferase- containing complexes.

Helmlinger D, Hardy S, Eberlin A, Devys D, Tora L. Helmlinger D, et al. Biochem Soc Symp. 2006;(73):155-63. doi: 10.1042/bss0730155. Biochem Soc Symp. 2006. PMID: 16626296

10

Transcriptional alterations and chromatin remodeling in polyglutamine diseases.

Helmlinger D, Tora L, Devys D. Helmlinger D, et al. Trends Genet. 2006 Oct;22(10):562-70. doi: 10.1016/j.tig.2006.07.010. Epub 2006 Sep 5. Trends Genet. 2006. PMID: 16911843 Review.

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