Kuehl WM - Search Results

1

Overexpression of c-maf is a frequent oncogenic event in multiple myeloma that promotes proliferation and pathological interactions with bone marrow stroma.

Hurt EM, Wiestner A, Rosenwald A, Shaffer AL, Campo E, Grogan T, Bergsagel PL, Kuehl WM, Staudt LM. Hurt EM, et al. Among authors: kuehl wm. Cancer Cell. 2004 Feb;5(2):191-9. doi: 10.1016/s1535-6108(04)00019-4. Cancer Cell. 2004. PMID: 14998494 Free article.

2

Multiple myeloma: evolving genetic events and host interactions.

Kuehl WM, Bergsagel PL. Kuehl WM, et al. Nat Rev Cancer. 2002 Mar;2(3):175-87. doi: 10.1038/nrc746. Nat Rev Cancer. 2002. PMID: 11990854 Review.

3

Early genetic events provide the basis for a clinical classification of multiple myeloma.

Kuehl WM, Bergsagel PL. Kuehl WM, et al. Hematology Am Soc Hematol Educ Program. 2005:346-52. doi: 10.1182/asheducation-2005.1.346. Hematology Am Soc Hematol Educ Program. 2005. PMID: 16304402

4

Frequent engagement of the classical and alternative NF-kappaB pathways by diverse genetic abnormalities in multiple myeloma.

Annunziata CM, Davis RE, Demchenko Y, Bellamy W, Gabrea A, Zhan F, Lenz G, Hanamura I, Wright G, Xiao W, Dave S, Hurt EM, Tan B, Zhao H, Stephens O, Santra M, Williams DR, Dang L, Barlogie B, Shaughnessy JD Jr, Kuehl WM, Staudt LM. Annunziata CM, et al. Among authors: kuehl wm. Cancer Cell. 2007 Aug;12(2):115-30. doi: 10.1016/j.ccr.2007.07.004. Cancer Cell. 2007. PMID: 17692804 Free PMC article.

5

Characterization of MYC translocations in multiple myeloma cell lines.

Dib A, Gabrea A, Glebov OK, Bergsagel PL, Kuehl WM. Dib A, et al. Among authors: kuehl wm. J Natl Cancer Inst Monogr. 2008;(39):25-31. doi: 10.1093/jncimonographs/lgn011. J Natl Cancer Inst Monogr. 2008. PMID: 18647998 Free PMC article.

6

A mechanistic rationale for MEK inhibitor therapy in myeloma based on blockade of MAF oncogene expression.

Annunziata CM, Hernandez L, Davis RE, Zingone A, Lamy L, Lam LT, Hurt EM, Shaffer AL, Kuehl WM, Staudt LM. Annunziata CM, et al. Among authors: kuehl wm. Blood. 2011 Feb 24;117(8):2396-404. doi: 10.1182/blood-2010-04-278788. Epub 2010 Dec 16. Blood. 2011. PMID: 21163924 Free PMC article.

7

Molecular pathogenesis of multiple myeloma and its premalignant precursor.

Kuehl WM, Bergsagel PL. Kuehl WM, et al. J Clin Invest. 2012 Oct;122(10):3456-63. doi: 10.1172/JCI61188. Epub 2012 Oct 1. J Clin Invest. 2012. PMID: 23023717 Free PMC article. Review.

8

Frequent occurrence of large duplications at reciprocal genomic rearrangement breakpoints in multiple myeloma and other tumors.

Demchenko Y, Roschke A, Chen WD, Asmann Y, Bergsagel PL, Kuehl WM. Demchenko Y, et al. Among authors: kuehl wm. Nucleic Acids Res. 2016 Sep 30;44(17):8189-98. doi: 10.1093/nar/gkw527. Epub 2016 Jun 27. Nucleic Acids Res. 2016. PMID: 27353332 Free PMC article.

9

The enigma of ectopic expression of FGFR3 in multiple myeloma: a critical initiating event or just a target for mutational activation during tumor progression.

Chesi M, Bergsagel PL, Kuehl WM. Chesi M, et al. Among authors: kuehl wm. Curr Opin Hematol. 2002 Jul;9(4):288-93. doi: 10.1097/00062752-200207000-00005. Curr Opin Hematol. 2002. PMID: 12042702 Review.

10

Critical roles for immunoglobulin translocations and cyclin D dysregulation in multiple myeloma.

Bergsagel PL, Kuehl WM. Bergsagel PL, et al. Among authors: kuehl wm. Immunol Rev. 2003 Aug;194:96-104. doi: 10.1034/j.1600-065x.2003.00052.x. Immunol Rev. 2003. PMID: 12846810 Review.

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