Jauch KW - Search Results

1

Blockage of 2-deoxy-D-ribose-induced angiogenesis with rapamycin counteracts a thymidine phosphorylase-based escape mechanism available for colon cancer under 5-fluorouracil therapy.

Seeliger H, Guba M, Koehl GE, Doenecke A, Steinbauer M, Bruns CJ, Wagner C, Frank E, Jauch KW, Geissler EK. Seeliger H, et al. Among authors: jauch kw. Clin Cancer Res. 2004 Mar 1;10(5):1843-52. doi: 10.1158/1078-0432.ccr-1176-3. Clin Cancer Res. 2004. PMID: 15014039

2

Rapamycin inhibits primary and metastatic tumor growth by antiangiogenesis: involvement of vascular endothelial growth factor.

Guba M, von Breitenbuch P, Steinbauer M, Koehl G, Flegel S, Hornung M, Bruns CJ, Zuelke C, Farkas S, Anthuber M, Jauch KW, Geissler EK. Guba M, et al. Among authors: jauch kw. Nat Med. 2002 Feb;8(2):128-35. doi: 10.1038/nm0202-128. Nat Med. 2002. PMID: 11821896

3

Rapamycin-induced endothelial cell death and tumor vessel thrombosis potentiate cytotoxic therapy against pancreatic cancer.

Bruns CJ, Koehl GE, Guba M, Yezhelyev M, Steinbauer M, Seeliger H, Schwend A, Hoehn A, Jauch KW, Geissler EK. Bruns CJ, et al. Among authors: jauch kw. Clin Cancer Res. 2004 Mar 15;10(6):2109-19. doi: 10.1158/1078-0432.ccr-03-0502. Clin Cancer Res. 2004. PMID: 15041732

4

Rapamycin protects allografts from rejection while simultaneously attacking tumors in immunosuppressed mice.

Koehl GE, Andrassy J, Guba M, Richter S, Kroemer A, Scherer MN, Steinbauer M, Graeb C, Schlitt HJ, Jauch KW, Geissler EK. Koehl GE, et al. Among authors: jauch kw. Transplantation. 2004 May 15;77(9):1319-26. doi: 10.1097/00007890-200405150-00002. Transplantation. 2004. PMID: 15167584

5

Dosing of rapamycin is critical to achieve an optimal antiangiogenic effect against cancer.

Guba M, Koehl GE, Neppl E, Doenecke A, Steinbauer M, Schlitt HJ, Jauch KW, Geissler EK. Guba M, et al. Among authors: jauch kw. Transpl Int. 2005 Jan;18(1):89-94. doi: 10.1111/j.1432-2277.2004.00026.x. Transpl Int. 2005. PMID: 15612989 Free article.

6

Role of mTOR in solid tumor systems: a therapeutical target against primary tumor growth, metastases, and angiogenesis.

Seeliger H, Guba M, Kleespies A, Jauch KW, Bruns CJ. Seeliger H, et al. Among authors: jauch kw. Cancer Metastasis Rev. 2007 Dec;26(3-4):611-21. doi: 10.1007/s10555-007-9077-8. Cancer Metastasis Rev. 2007. PMID: 17713840 Review.

7

Antiangiogenic therapy with mammalian target of rapamycin inhibitor RAD001 (Everolimus) increases radiosensitivity in solid cancer.

Manegold PC, Paringer C, Kulka U, Krimmel K, Eichhorn ME, Wilkowski R, Jauch KW, Guba M, Bruns CJ. Manegold PC, et al. Among authors: jauch kw. Clin Cancer Res. 2008 Feb 1;14(3):892-900. doi: 10.1158/1078-0432.CCR-07-0955. Clin Cancer Res. 2008. PMID: 18245553

8

The antineoplastic drug Paclitaxel has immunosuppressive properties that can effectively promote allograft survival in a rat heart transplant model.

Tange S, Scherer MN, Graeb C, Weiss T, Justl M, Frank E, Andrassy J, Jauch KW, Geissler EK. Tange S, et al. Among authors: jauch kw. Transplantation. 2002 Jan 27;73(2):216-23. doi: 10.1097/00007890-200201270-00011. Transplantation. 2002. PMID: 11821733

9

GFP-transfected tumor cells are useful in examining early metastasis in vivo, but immune reaction precludes long-term tumor development studies in immunocompetent mice.

Steinbauer M, Guba M, Cernaianu G, Köhl G, Cetto M, Kunz-Schughart LA, Geissler EK, Falk W, Jauch KW. Steinbauer M, et al. Among authors: jauch kw. Clin Exp Metastasis. 2003;20(2):135-41. doi: 10.1023/a:1022618909921. Clin Exp Metastasis. 2003. PMID: 12705634

10

Vascular endothelial growth factor in colorectal cancer.

Guba M, Seeliger H, Kleespies A, Jauch KW, Bruns C. Guba M, et al. Among authors: jauch kw. Int J Colorectal Dis. 2004 Nov;19(6):510-7. doi: 10.1007/s00384-003-0576-y. Epub 2004 Mar 4. Int J Colorectal Dis. 2004. PMID: 14999511 Review.

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