Oosterhoff D - Search Results

1

Pronounced antitumor efficacy by extracellular activation of a doxorubicin-glucuronide prodrug after adenoviral vector-mediated expression of a human antibody-enzyme fusion protein.

de Graaf M, Pinedo HM, Oosterhoff D, van der Meulen-Muileman IH, Gerritsen WR, Haisma HJ, Boven E. de Graaf M, et al. Among authors: oosterhoff d. Hum Gene Ther. 2004 Mar;15(3):229-38. doi: 10.1089/104303404322886084. Hum Gene Ther. 2004. PMID: 15018732

2

Gene-directed enzyme prodrug therapy for osteosarcoma: sensitization to CPT-11 in vitro and in vivo by adenoviral delivery of a gene encoding secreted carboxylesterase-2.

Oosterhoff D, Witlox MA, van Beusechem VW, Haisma HJ, Schaap GR, Bras J, Kruyt FA, Molenaar B, Boven E, Wuisman PI, Pinedo HM, Gerritsen WR. Oosterhoff D, et al. Mol Cancer Ther. 2003 Aug;2(8):765-71. Mol Cancer Ther. 2003. PMID: 12939466

3

A fully human anti-Ep-CAM scFv-beta-glucuronidase fusion protein for selective chemotherapy with a glucuronide prodrug.

de Graaf M, Boven E, Oosterhoff D, van der Meulen-Muileman IH, Huls GA, Gerritsen WR, Haisma HJ, Pinedo HM. de Graaf M, et al. Among authors: oosterhoff d. Br J Cancer. 2002 Mar 4;86(5):811-8. doi: 10.1038/sj.bjc.6600143. Br J Cancer. 2002. PMID: 11875747 Free PMC article.

4

Secreted and tumour targeted human carboxylesterase for activation of irinotecan.

Oosterhoff D, Pinedo HM, van der Meulen IH, de Graaf M, Sone T, Kruyt FA, van Beusechem VW, Haisma HJ, Gerritsen WR. Oosterhoff D, et al. Br J Cancer. 2002 Sep 9;87(6):659-64. doi: 10.1038/sj.bjc.6600519. Br J Cancer. 2002. PMID: 12237777 Free PMC article.

5

Gene-directed enzyme prodrug therapy with carboxylesterase enhances the anticancer efficacy of the conditionally replicating adenovirus AdDelta24.

Oosterhoff D, Pinedo HM, Witlox MA, Carette JE, Gerritsen WR, van Beusechem VW. Oosterhoff D, et al. Gene Ther. 2005 Jun;12(12):1011-8. doi: 10.1038/sj.gt.3302492. Gene Ther. 2005. PMID: 15729367

6

Adenoviral vector-mediated expression of a gene encoding secreted, EpCAM-targeted carboxylesterase-2 sensitises colon cancer spheroids to CPT-11.

Oosterhoff D, Overmeer RM, de Graaf M, van der Meulen IH, Giaccone G, van Beusechem VW, Haisma HJ, Pinedo HM, Gerritsen WR. Oosterhoff D, et al. Br J Cancer. 2005 Mar 14;92(5):882-7. doi: 10.1038/sj.bjc.6602362. Br J Cancer. 2005. PMID: 15756257 Free PMC article.

7

Potent antitumor immunity generated by a CD40-targeted adenoviral vaccine.

Hangalapura BN, Oosterhoff D, de Groot J, Boon L, Tüting T, van den Eertwegh AJ, Gerritsen WR, van Beusechem VW, Pereboev A, Curiel DT, Scheper RJ, de Gruijl TD. Hangalapura BN, et al. Among authors: oosterhoff d. Cancer Res. 2011 Sep 1;71(17):5827-37. doi: 10.1158/0008-5472.CAN-11-0804. Epub 2011 Jul 11. Cancer Res. 2011. PMID: 21747119 Free article.

8

A postmigrational switch among skin-derived dendritic cells to a macrophage-like phenotype is predetermined by the intracutaneous cytokine balance.

de Gruijl TD, Sombroek CC, Lougheed SM, Oosterhoff D, Buter J, van den Eertwegh AJ, Scheper RJ, Pinedo HM. de Gruijl TD, et al. Among authors: oosterhoff d. J Immunol. 2006 Jun 15;176(12):7232-42. doi: 10.4049/jimmunol.176.12.7232. J Immunol. 2006. PMID: 16751366

9

IL-10 conditioning of human skin affects the distribution of migratory dendritic cell subsets and functional T cell differentiation.

Lindenberg JJ, Oosterhoff D, Sombroek CC, Lougheed SM, Hooijberg E, Stam AG, Santegoets SJ, Tijssen HJ, Buter J, Pinedo HM, van den Eertwegh AJ, Scheper RJ, Koenen HJ, van de Ven R, de Gruijl TD. Lindenberg JJ, et al. Among authors: oosterhoff d. PLoS One. 2013 Jul 18;8(7):e70237. doi: 10.1371/journal.pone.0070237. Print 2013. PLoS One. 2013. PMID: 23875023 Free PMC article.

10

Sunitinib-induced myeloid lineage redistribution in renal cell cancer patients: CD1c+ dendritic cell frequency predicts progression-free survival.

van Cruijsen H, van der Veldt AA, Vroling L, Oosterhoff D, Broxterman HJ, Scheper RJ, Giaccone G, Haanen JB, van den Eertwegh AJ, Boven E, Hoekman K, de Gruijl TD. van Cruijsen H, et al. Among authors: oosterhoff d. Clin Cancer Res. 2008 Sep 15;14(18):5884-92. doi: 10.1158/1078-0432.CCR-08-0656. Clin Cancer Res. 2008. PMID: 18794101

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