van der Meulen-Muileman IH - Search Results

1

Pronounced antitumor efficacy by extracellular activation of a doxorubicin-glucuronide prodrug after adenoviral vector-mediated expression of a human antibody-enzyme fusion protein.

de Graaf M, Pinedo HM, Oosterhoff D, van der Meulen-Muileman IH, Gerritsen WR, Haisma HJ, Boven E. de Graaf M, et al. Hum Gene Ther. 2004 Mar;15(3):229-38. doi: 10.1089/104303404322886084. Hum Gene Ther. 2004. PMID: 15018732

2

Synthesis and biological activity of beta-glucuronyl carbamate-based prodrugs of paclitaxel as potential candidates for ADEPT.

de Bont DB, Leenders RG, Haisma HJ, van der Meulen-Muileman I, Scheeren HW. de Bont DB, et al. Bioorg Med Chem. 1997 Feb;5(2):405-14. doi: 10.1016/s0968-0896(96)00249-0. Bioorg Med Chem. 1997. PMID: 9061205

3

Distribution and pharmacokinetics of the prodrug daunorubicin-GA3 in nude mice bearing human ovarian cancer xenografts.

Houba PH, Boven E, van der Meulen-Muileman IH, Leenders RG, Scheeren JW, Pinedo HM, Haisma HJ. Houba PH, et al. Biochem Pharmacol. 1999 Mar 15;57(6):673-80. doi: 10.1016/s0006-2952(98)00343-8. Biochem Pharmacol. 1999. PMID: 10037453

4

Novel anthracycline-spacer-beta-glucuronide,-beta-glucoside, and -beta-galactoside prodrugs for application in selective chemotherapy.

Leenders RG, Damen EW, Bijsterveld EJ, Scheeren HW, Houba PH, van der Meulen-Muileman IH, Boven E, Haisma HJ. Leenders RG, et al. Bioorg Med Chem. 1999 Aug;7(8):1597-610. doi: 10.1016/s0968-0896(99)00095-4. Bioorg Med Chem. 1999. PMID: 10482452

5

A novel doxorubicin-glucuronide prodrug DOX-GA3 for tumour-selective chemotherapy: distribution and efficacy in experimental human ovarian cancer.

Houba PH, Boven E, van der Meulen-Muileman IH, Leenders RG, Scheeren JW, Pinedo HM, Haisma HJ. Houba PH, et al. Br J Cancer. 2001 Feb;84(4):550-7. doi: 10.1054/bjoc.2000.1640. Br J Cancer. 2001. PMID: 11207053 Free PMC article.

6

Pronounced antitumor efficacy of doxorubicin when given as the prodrug DOX-GA3 in combination with a monoclonal antibody beta-glucuronidase conjugate.

Houba PH, Boven E, van der Meulen-Muileman IH, Leenders RG, Scheeren JW, Pinedo HM, Haisma HJ. Houba PH, et al. Int J Cancer. 2001 Feb 15;91(4):550-4. doi: 10.1002/1097-0215(200002)9999:9999<::aid-ijc1075>3.0.co;2-l. Int J Cancer. 2001. PMID: 11251980

7

Cloning and characterization of human liver cytosolic beta-glycosidase.

de Graaf M, van Veen IC, van der Meulen-Muileman IH, Gerritsen WR, Pinedo HM, Haisma HJ. de Graaf M, et al. Biochem J. 2001 Jun 15;356(Pt 3):907-10. doi: 10.1042/0264-6021:3560907. Biochem J. 2001. PMID: 11389701 Free PMC article.

8

A fully human anti-Ep-CAM scFv-beta-glucuronidase fusion protein for selective chemotherapy with a glucuronide prodrug.

de Graaf M, Boven E, Oosterhoff D, van der Meulen-Muileman IH, Huls GA, Gerritsen WR, Haisma HJ, Pinedo HM. de Graaf M, et al. Br J Cancer. 2002 Mar 4;86(5):811-8. doi: 10.1038/sj.bjc.6600143. Br J Cancer. 2002. PMID: 11875747 Free PMC article.

9

Expression of scFvs and scFv fusion proteins in eukaryotic cells.

de Graaf M, van der Meulen-Muileman IH, Pinedo HM, Haisma HJ. de Graaf M, et al. Methods Mol Biol. 2002;178:379-87. doi: 10.1385/1-59259-240-6:379. Methods Mol Biol. 2002. PMID: 11968507 Review. No abstract available.

10

Differential effects of combined Ad5- delta 24RGD and radiation therapy in in vitro versus in vivo models of malignant glioma.

Lamfers ML, Idema S, Bosscher L, Heukelom S, Moeniralm S, van der Meulen-Muileman IH, Overmeer RM, van der Valk P, van Beusechem VW, Gerritsen WR, Vandertop WP, Dirven CM. Lamfers ML, et al. Clin Cancer Res. 2007 Dec 15;13(24):7451-8. doi: 10.1158/1078-0432.CCR-07-1265. Clin Cancer Res. 2007. PMID: 18094429

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