Mathews PM - Search Results

1

Co-expressed presenilin 1 NTF and CTF form functional gamma-secretase complexes in cells devoid of full-length protein.

Laudon H, Mathews PM, Karlström H, Bergman A, Farmery MR, Nixon RA, Winblad B, Gandy SE, Lendahl U, Lundkvist J, Näslund J. Laudon H, et al. Among authors: mathews pm. J Neurochem. 2004 Apr;89(1):44-53. doi: 10.1046/j.1471-4159.2003.02298.x. J Neurochem. 2004. PMID: 15030388 Free article.

2

Functional domains in presenilin 1: the Tyr-288 residue controls gamma-secretase activity and endoproteolysis.

Laudon H, Karlström H, Mathews PM, Farmery MR, Gandy SE, Lundkvist J, Lendahl U, Näslund J. Laudon H, et al. Among authors: mathews pm. J Biol Chem. 2004 Jun 4;279(23):23925-32. doi: 10.1074/jbc.M401277200. Epub 2004 Mar 29. J Biol Chem. 2004. PMID: 15051718 Free article.

3

Alzheimer's presenilin 1 modulates sorting of APP and its carboxyl-terminal fragments in cerebral neurons in vivo.

Gandy S, Zhang YW, Ikin A, Schmidt SD, Bogush A, Levy E, Sheffield R, Nixon RA, Liao FF, Mathews PM, Xu H, Ehrlich ME. Gandy S, et al. Among authors: mathews pm. J Neurochem. 2007 Aug;102(3):619-26. doi: 10.1111/j.1471-4159.2007.04587.x. J Neurochem. 2007. PMID: 17630980 Free article.

4

Macroautophagy--a novel Beta-amyloid peptide-generating pathway activated in Alzheimer's disease.

Yu WH, Cuervo AM, Kumar A, Peterhoff CM, Schmidt SD, Lee JH, Mohan PS, Mercken M, Farmery MR, Tjernberg LO, Jiang Y, Duff K, Uchiyama Y, Näslund J, Mathews PM, Cataldo AM, Nixon RA. Yu WH, et al. Among authors: mathews pm. J Cell Biol. 2005 Oct 10;171(1):87-98. doi: 10.1083/jcb.200505082. Epub 2005 Oct 3. J Cell Biol. 2005. PMID: 16203860 Free PMC article.

5

Cellular expression and proteolytic processing of presenilin proteins is developmentally regulated during neuronal differentiation.

Capell A, Saffrich R, Olivo JC, Meyn L, Walter J, Grünberg J, Mathews P, Nixon R, Dotti C, Haass C. Capell A, et al. J Neurochem. 1997 Dec;69(6):2432-40. doi: 10.1046/j.1471-4159.1997.69062432.x. J Neurochem. 1997. PMID: 9375676 Free article.

6

Mature glycosylation and trafficking of nicastrin modulate its binding to presenilins.

Yang DS, Tandon A, Chen F, Yu G, Yu H, Arawaka S, Hasegawa H, Duthie M, Schmidt SD, Ramabhadran TV, Nixon RA, Mathews PM, Gandy SE, Mount HT, St George-Hyslop P, Fraser PE. Yang DS, et al. Among authors: mathews pm. J Biol Chem. 2002 Aug 2;277(31):28135-42. doi: 10.1074/jbc.M110871200. Epub 2002 May 24. J Biol Chem. 2002. PMID: 12032140 Free article.

7

Tissue processing prior to protein analysis and amyloid-beta quantitation.

Schmidt SD, Jiang Y, Nixon RA, Mathews PM. Schmidt SD, et al. Among authors: mathews pm. Methods Mol Biol. 2005;299:267-78. doi: 10.1385/1-59259-874-9:267. Methods Mol Biol. 2005. PMID: 15980611

8

ELISA method for measurement of amyloid-beta levels.

Schmidt SD, Nixon RA, Mathews PM. Schmidt SD, et al. Among authors: mathews pm. Methods Mol Biol. 2005;299:279-97. doi: 10.1385/1-59259-874-9:279. Methods Mol Biol. 2005. PMID: 15980612

9

Age-dependent dysregulation of brain amyloid precursor protein in the Ts65Dn Down syndrome mouse model.

Choi JH, Berger JD, Mazzella MJ, Morales-Corraliza J, Cataldo AM, Nixon RA, Ginsberg SD, Levy E, Mathews PM. Choi JH, et al. Among authors: mathews pm. J Neurochem. 2009 Sep;110(6):1818-27. doi: 10.1111/j.1471-4159.2009.06277.x. Epub 2009 Jul 10. J Neurochem. 2009. PMID: 19619138 Free PMC article.

10

Tissue processing prior to analysis of Alzheimer's disease associated proteins and metabolites, including Aβ.

Schmidt SD, Nixon RA, Mathews PM. Schmidt SD, et al. Among authors: mathews pm. Methods Mol Biol. 2012;849:493-506. doi: 10.1007/978-1-61779-551-0_33. Methods Mol Biol. 2012. PMID: 22528111

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