Chen WD - Search Results

1

Epigenetic inactivation of SFRP genes allows constitutive WNT signaling in colorectal cancer.

Suzuki H, Watkins DN, Jair KW, Schuebel KE, Markowitz SD, Chen WD, Pretlow TP, Yang B, Akiyama Y, Van Engeland M, Toyota M, Tokino T, Hinoda Y, Imai K, Herman JG, Baylin SB. Suzuki H, et al. Among authors: chen wd. Nat Genet. 2004 Apr;36(4):417-22. doi: 10.1038/ng1330. Epub 2004 Mar 14. Nat Genet. 2004. PMID: 15034581

2

A genomic screen for genes upregulated by demethylation and histone deacetylase inhibition in human colorectal cancer.

Suzuki H, Gabrielson E, Chen W, Anbazhagan R, van Engeland M, Weijenberg MP, Herman JG, Baylin SB. Suzuki H, et al. Nat Genet. 2002 Jun;31(2):141-9. doi: 10.1038/ng892. Epub 2002 May 6. Nat Genet. 2002. PMID: 11992124

3

A stem cell-like chromatin pattern may predispose tumor suppressor genes to DNA hypermethylation and heritable silencing.

Ohm JE, McGarvey KM, Yu X, Cheng L, Schuebel KE, Cope L, Mohammad HP, Chen W, Daniel VC, Yu W, Berman DM, Jenuwein T, Pruitt K, Sharkis SJ, Watkins DN, Herman JG, Baylin SB. Ohm JE, et al. Nat Genet. 2007 Feb;39(2):237-42. doi: 10.1038/ng1972. Epub 2007 Jan 9. Nat Genet. 2007. PMID: 17211412 Free PMC article.

4

Comparing the DNA hypermethylome with gene mutations in human colorectal cancer.

Schuebel KE, Chen W, Cope L, Glöckner SC, Suzuki H, Yi JM, Chan TA, Van Neste L, Van Criekinge W, van den Bosch S, van Engeland M, Ting AH, Jair K, Yu W, Toyota M, Imai K, Ahuja N, Herman JG, Baylin SB. Schuebel KE, et al. PLoS Genet. 2007 Sep;3(9):1709-23. doi: 10.1371/journal.pgen.0030157. Epub 2007 Jul 31. PLoS Genet. 2007. PMID: 17892325 Free PMC article.

5

CIMPle origin for promoter hypermethylation in colorectal cancer?

Schuebel K, Chen W, Baylin SB. Schuebel K, et al. Nat Genet. 2006 Jul;38(7):738-40. doi: 10.1038/ng0706-738. Nat Genet. 2006. PMID: 16804535 No abstract available.

6

Convergence of mutation and epigenetic alterations identifies common genes in cancer that predict for poor prognosis.

Chan TA, Glockner S, Yi JM, Chen W, Van Neste L, Cope L, Herman JG, Velculescu V, Schuebel KE, Ahuja N, Baylin SB. Chan TA, et al. PLoS Med. 2008 May 27;5(5):e114. doi: 10.1371/journal.pmed.0050114. PLoS Med. 2008. PMID: 18507500 Free PMC article.

7

Detection in fecal DNA of colon cancer-specific methylation of the nonexpressed vimentin gene.

Chen WD, Han ZJ, Skoletsky J, Olson J, Sah J, Myeroff L, Platzer P, Lu S, Dawson D, Willis J, Pretlow TP, Lutterbaugh J, Kasturi L, Willson JK, Rao JS, Shuber A, Markowitz SD. Chen WD, et al. J Natl Cancer Inst. 2005 Aug 3;97(15):1124-32. doi: 10.1093/jnci/dji204. J Natl Cancer Inst. 2005. PMID: 16077070

8

Sensitive digital quantification of DNA methylation in clinical samples.

Li M, Chen WD, Papadopoulos N, Goodman SN, Bjerregaard NC, Laurberg S, Levin B, Juhl H, Arber N, Moinova H, Durkee K, Schmidt K, He Y, Diehl F, Velculescu VE, Zhou S, Diaz LA Jr, Kinzler KW, Markowitz SD, Vogelstein B. Li M, et al. Among authors: chen wd. Nat Biotechnol. 2009 Sep;27(9):858-63. doi: 10.1038/nbt.1559. Epub 2009 Aug 16. Nat Biotechnol. 2009. PMID: 19684580 Free PMC article.

9

Comparative lesion sequencing provides insights into tumor evolution.

Jones S, Chen WD, Parmigiani G, Diehl F, Beerenwinkel N, Antal T, Traulsen A, Nowak MA, Siegel C, Velculescu VE, Kinzler KW, Vogelstein B, Willis J, Markowitz SD. Jones S, et al. Among authors: chen wd. Proc Natl Acad Sci U S A. 2008 Mar 18;105(11):4283-8. doi: 10.1073/pnas.0712345105. Epub 2008 Mar 12. Proc Natl Acad Sci U S A. 2008. PMID: 18337506 Free PMC article.

10

CpG island methylation in aberrant crypt foci and cancers from the same patients.

Luo L, Chen WD, Pretlow TP. Luo L, et al. Among authors: chen wd. Int J Cancer. 2005 Jul 10;115(5):747-51. doi: 10.1002/ijc.20936. Int J Cancer. 2005. PMID: 15704093

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