Watkins DN - Search Results

1

Epigenetic inactivation of SFRP genes allows constitutive WNT signaling in colorectal cancer.

Suzuki H, Watkins DN, Jair KW, Schuebel KE, Markowitz SD, Chen WD, Pretlow TP, Yang B, Akiyama Y, Van Engeland M, Toyota M, Tokino T, Hinoda Y, Imai K, Herman JG, Baylin SB. Suzuki H, et al. Among authors: watkins dn. Nat Genet. 2004 Apr;36(4):417-22. doi: 10.1038/ng1330. Epub 2004 Mar 14. Nat Genet. 2004. PMID: 15034581

2

Inactivation of the DNA repair gene O6-methylguanine-DNA methyltransferase by promoter hypermethylation is associated with G to A mutations in K-ras in colorectal tumorigenesis.

Esteller M, Toyota M, Sanchez-Cespedes M, Capella G, Peinado MA, Watkins DN, Issa JP, Sidransky D, Baylin SB, Herman JG. Esteller M, et al. Among authors: watkins dn. Cancer Res. 2000 May 1;60(9):2368-71. Cancer Res. 2000. PMID: 10811111

3

Mammalian Scratch: a neural-specific Snail family transcriptional repressor.

Nakakura EK, Watkins DN, Schuebel KE, Sriuranpong V, Borges MW, Nelkin BD, Ball DW. Nakakura EK, et al. Among authors: watkins dn. Proc Natl Acad Sci U S A. 2001 Mar 27;98(7):4010-5. doi: 10.1073/pnas.051014098. Epub 2001 Mar 13. Proc Natl Acad Sci U S A. 2001. PMID: 11274425 Free PMC article.

4

p14ARF silencing by promoter hypermethylation mediates abnormal intracellular localization of MDM2.

Esteller M, Cordon-Cardo C, Corn PG, Meltzer SJ, Pohar KS, Watkins DN, Capella G, Peinado MA, Matias-Guiu X, Prat J, Baylin SB, Herman JG. Esteller M, et al. Among authors: watkins dn. Cancer Res. 2001 Apr 1;61(7):2816-21. Cancer Res. 2001. PMID: 11306450

5

Heterozygous disruption of Hic1 predisposes mice to a gender-dependent spectrum of malignant tumors.

Chen WY, Zeng X, Carter MG, Morrell CN, Chiu Yen RW, Esteller M, Watkins DN, Herman JG, Mankowski JL, Baylin SB. Chen WY, et al. Among authors: watkins dn. Nat Genet. 2003 Feb;33(2):197-202. doi: 10.1038/ng1077. Epub 2003 Jan 21. Nat Genet. 2003. PMID: 12539045

6

Hedgehog signalling within airway epithelial progenitors and in small-cell lung cancer.

Watkins DN, Berman DM, Burkholder SG, Wang B, Beachy PA, Baylin SB. Watkins DN, et al. Nature. 2003 Mar 20;422(6929):313-7. doi: 10.1038/nature01493. Epub 2003 Mar 5. Nature. 2003. PMID: 12629553

7

Hedgehog signaling: progenitor phenotype in small-cell lung cancer.

Watkins DN, Berman DM, Baylin SB. Watkins DN, et al. Cell Cycle. 2003 May-Jun;2(3):196-8. Cell Cycle. 2003. PMID: 12734424 Review.

8

Widespread requirement for Hedgehog ligand stimulation in growth of digestive tract tumours.

Berman DM, Karhadkar SS, Maitra A, Montes De Oca R, Gerstenblith MR, Briggs K, Parker AR, Shimada Y, Eshleman JR, Watkins DN, Beachy PA. Berman DM, et al. Among authors: watkins dn. Nature. 2003 Oct 23;425(6960):846-51. doi: 10.1038/nature01972. Epub 2003 Sep 14. Nature. 2003. PMID: 14520411

9

Inhibition of SIRT1 reactivates silenced cancer genes without loss of promoter DNA hypermethylation.

Pruitt K, Zinn RL, Ohm JE, McGarvey KM, Kang SH, Watkins DN, Herman JG, Baylin SB. Pruitt K, et al. Among authors: watkins dn. PLoS Genet. 2006 Mar;2(3):e40. doi: 10.1371/journal.pgen.0020040. Epub 2006 Mar 31. PLoS Genet. 2006. PMID: 16596166 Free PMC article.

10

A stem cell-like chromatin pattern may predispose tumor suppressor genes to DNA hypermethylation and heritable silencing.

Ohm JE, McGarvey KM, Yu X, Cheng L, Schuebel KE, Cope L, Mohammad HP, Chen W, Daniel VC, Yu W, Berman DM, Jenuwein T, Pruitt K, Sharkis SJ, Watkins DN, Herman JG, Baylin SB. Ohm JE, et al. Among authors: watkins dn. Nat Genet. 2007 Feb;39(2):237-42. doi: 10.1038/ng1972. Epub 2007 Jan 9. Nat Genet. 2007. PMID: 17211412 Free PMC article.

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