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Page 1
Identification and characterization of a potent, selective, and orally active antagonist of the CC chemokine receptor-1.
Liang M, Mallari C, Rosser M, Ng HP, May K, Monahan S, Bauman JG, Islam I, Ghannam A, Buckman B, Shaw K, Wei GP, Xu W, Zhao Z, Ho E, Shen J, Oanh H, Subramanyam B, Vergona R, Taub D, Dunning L, Harvey S, Snider RM, Hesselgesser J, Morrissey MM, Perez HD. Liang M, et al. Among authors: mallari c. J Biol Chem. 2000 Jun 23;275(25):19000-8. doi: 10.1074/jbc.M001222200. J Biol Chem. 2000. PMID: 10748002 Free article.
Discovery of selective urokinase plasminogen activator (uPA) inhibitors as a potential treatment for multiple sclerosis.
Islam I, Yuan S, West CW, Adler M, Bothe U, Bryant J, Chang Z, Chu K, Emayan K, Gualtieri G, Ho E, Light D, Mallari C, Morser J, Phillips G, Schaefer C, Sukovich D, Whitlow M, Chen D, Buckman BO. Islam I, et al. Among authors: mallari c. Bioorg Med Chem Lett. 2018 Nov 1;28(20):3372-3375. doi: 10.1016/j.bmcl.2018.09.001. Epub 2018 Sep 5. Bioorg Med Chem Lett. 2018. PMID: 30201291
Differential inhibition of inducible T cell cytokine secretion by potent iron chelators.
Leung S, Holbrook A, King B, Lu HT, Evans V, Miyamoto N, Mallari C, Harvey S, Davey D, Ho E, Li WW, Parkinson J, Horuk R, Jaroch S, Berger M, Skuballa W, West C, Pulk R, Phillips G, Bryant J, Subramanyam B, Schaefer C, Salamon H, Lyons E, Schilling D, Seidel H, Kraetzschmar J, Snider M, Perez D. Leung S, et al. Among authors: mallari c. J Biomol Screen. 2005 Mar;10(2):157-67. doi: 10.1177/1087057104272394. J Biomol Screen. 2005. PMID: 15799959
Allosteric inhibitors of inducible nitric oxide synthase dimerization discovered via combinatorial chemistry.
McMillan K, Adler M, Auld DS, Baldwin JJ, Blasko E, Browne LJ, Chelsky D, Davey D, Dolle RE, Eagen KA, Erickson S, Feldman RI, Glaser CB, Mallari C, Morrissey MM, Ohlmeyer MH, Pan G, Parkinson JF, Phillips GB, Polokoff MA, Sigal NH, Vergona R, Whitlow M, Young TA, Devlin JJ. McMillan K, et al. Among authors: mallari c. Proc Natl Acad Sci U S A. 2000 Feb 15;97(4):1506-11. doi: 10.1073/pnas.97.4.1506. Proc Natl Acad Sci U S A. 2000. PMID: 10677491 Free PMC article.
A selective inducible NOS dimerization inhibitor prevents systemic, cardiac, and pulmonary hemodynamic dysfunction in endotoxemic mice.
Ichinose F, Hataishi R, Wu JC, Kawai N, Rodrigues AC, Mallari C, Post JM, Parkinson JF, Picard MH, Bloch KD, Zapol WM. Ichinose F, et al. Among authors: mallari c. Am J Physiol Heart Circ Physiol. 2003 Dec;285(6):H2524-30. doi: 10.1152/ajpheart.00530.2003. Epub 2003 Aug 7. Am J Physiol Heart Circ Physiol. 2003. PMID: 12907425 Free article.
21 results