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V599EB-RAF is an oncogene in melanocytes.
Wellbrock C, Ogilvie L, Hedley D, Karasarides M, Martin J, Niculescu-Duvaz D, Springer CJ, Marais R. Wellbrock C, et al. Cancer Res. 2004 Apr 1;64(7):2338-42. doi: 10.1158/0008-5472.can-03-3433. Cancer Res. 2004. PMID: 15059882
The RAF proteins take centre stage.
Wellbrock C, Karasarides M, Marais R. Wellbrock C, et al. Nat Rev Mol Cell Biol. 2004 Nov;5(11):875-85. doi: 10.1038/nrm1498. Nat Rev Mol Cell Biol. 2004. PMID: 15520807 Review.
Melanoma biology and new targeted therapy.
Gray-Schopfer V, Wellbrock C, Marais R. Gray-Schopfer V, et al. Among authors: wellbrock c. Nature. 2007 Feb 22;445(7130):851-7. doi: 10.1038/nature05661. Nature. 2007. PMID: 17314971 Review.
Effect of SMURF2 targeting on susceptibility to MEK inhibitors in melanoma.
Smith MP, Ferguson J, Arozarena I, Hayward R, Marais R, Chapman A, Hurlstone A, Wellbrock C. Smith MP, et al. Among authors: wellbrock c. J Natl Cancer Inst. 2013 Jan 2;105(1):33-46. doi: 10.1093/jnci/djs471. Epub 2012 Dec 17. J Natl Cancer Inst. 2013. PMID: 23250956 Free PMC article.
Inhibiting Drivers of Non-mutational Drug Tolerance Is a Salvage Strategy for Targeted Melanoma Therapy.
Smith MP, Brunton H, Rowling EJ, Ferguson J, Arozarena I, Miskolczi Z, Lee JL, Girotti MR, Marais R, Levesque MP, Dummer R, Frederick DT, Flaherty KT, Cooper ZA, Wargo JA, Wellbrock C. Smith MP, et al. Among authors: wellbrock c. Cancer Cell. 2016 Mar 14;29(3):270-284. doi: 10.1016/j.ccell.2016.02.003. Cancer Cell. 2016. PMID: 26977879 Free PMC article.
66 results