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Page 1
HIF1α Plays a Crucial Role in the Development of TFE3-Rearranged Renal Cell Carcinoma by Orchestrating a Metabolic Shift Toward Fatty Acid Synthesis.
Nishizawa H, Funasaki S, Ma W, Kubota Y, Watanabe K, Arima Y, Kuroda S, Ito T, Furuya M, Motoshima T, Nishiyama A, Mehanna S, Satou Y, Hasumi H, Jikuya R, Makiyama K, Tamura T, Oike Y, Tanaka Y, Suda T, Schmidt LS, Linehan WM, Baba M, Kamba T. Nishizawa H, et al. Among authors: schmidt ls. Genes Cells. 2025 Jan;30(1):e13195. doi: 10.1111/gtc.13195. Genes Cells. 2025. PMID: 39807625 Free PMC article.
SFPQ-TFE3 gene fusion reciprocally regulates mTORC1 activity and induces lineage plasticity in a novel mouse model of renal tumorigenesis.
Asrani K, Amaral A, Woo J, Abadchi SN, Vidotto T, Feng K, Liu HB, Kasbe M, Baba M, Oike Y, Outeda P, Watnick T, Rosenberg AZ, Schmidt LS, Linehan WM, Argani P, Lotan TL. Asrani K, et al. Among authors: schmidt ls. bioRxiv [Preprint]. 2024 Nov 22:2024.11.21.624702. doi: 10.1101/2024.11.21.624702. bioRxiv. 2024. PMID: 39605439 Free PMC article. Preprint.
Mycoplasma pneumoniae incidence, phenotype, and severity in children and adolescents in Denmark before, during, and after the COVID-19 pandemic: a nationwide multicentre population-based cohort study.
Dungu KHS, Holm M, Hartling U, Jensen LH, Nielsen AB, Schmidt LS, Toustrup LB, Hansen LH, Dahl KW, Matthesen KT, Nordholm AC, Uldum S, Emborg HD, Rytter MJH, Nygaard U. Dungu KHS, et al. Among authors: schmidt ls. Lancet Reg Health Eur. 2024 Oct 18;47:101103. doi: 10.1016/j.lanepe.2024.101103. eCollection 2024 Dec. Lancet Reg Health Eur. 2024. PMID: 39469091 Free PMC article.
Targeting NAD+ Metabolism Vulnerability in FH-Deficient Hereditary Leiomyomatosis and Renal Cell Carcinoma with the novel NAMPT Inhibitor OT-82.
Najera SS, Ricketts CJ, Schmidt LS, Medina JI, Saito K, Ileva L, Brender JR, James AM, Peer CJ, Gouker B, Karim BO, Chernova O, Wells C, Wei MH, Yang Y, Zhang X, Klumpp-Thomas C, Travers J, Chen L, Wilson KM, Issaq SH, Figg WD, Difilippantonio S, Kalen JD, Krishna MC, Thomas CJ, Ceribelli M, Heske CM, Crooks DR, Meier JL. Najera SS, et al. Among authors: schmidt ls. Mol Cancer Ther. 2024 Oct 14. doi: 10.1158/1535-7163.MCT-24-0225. Online ahead of print. Mol Cancer Ther. 2024. PMID: 39397296
Toward a CRISPR-based mouse model of Vhl-deficient clear cell kidney cancer: Initial experience and lessons learned.
Stransky LA, Gao W, Schmidt LS, Bi K, Ricketts CJ, Ramesh V, James A, Difilippantonio S, Ileva L, Kalen JD, Karim B, Jeon A, Morgan T, Warner AC, Turan S, Unite J, Tran B, Choudhari S, Zhao Y, Linn DE, Yun C, Dhandapani S, Parab V, Pinheiro EM, Morris N, He L, Vigeant SM, Pignon JC, Sticco-Ivins M, Signoretti S, Van Allen EM, Linehan WM, Kaelin WG Jr. Stransky LA, et al. Among authors: schmidt ls. Proc Natl Acad Sci U S A. 2024 Oct 8;121(41):e2408549121. doi: 10.1073/pnas.2408549121. Epub 2024 Oct 4. Proc Natl Acad Sci U S A. 2024. PMID: 39365820 Free PMC article.
A novel pathogenic germline chromosome 3 inversion in von Hippel-Lindau disease.
Vocke CD, Ricketts CJ, Pack S, Raffeld M, Hewitt S, Lebensohn AP, O'Brien L, Gautam R, Reynolds K, Schmidt LS, Choo K, Kenigsberg A, Gurram S, Chew EY, Nilubol N, Chittaboina P, Merino MJ, Ball MW, Linehan WM. Vocke CD, et al. Among authors: schmidt ls. J Med Genet. 2024 Oct 23;61(11):1026-1030. doi: 10.1136/jmg-2024-110202. J Med Genet. 2024. PMID: 39317422 Free PMC article.
Oral versus intravenous empirical antibiotics in children and adolescents with uncomplicated bone and joint infections: a nationwide, randomised, controlled, non-inferiority trial in Denmark.
Nielsen AB, Holm M, Lindhard MS, Glenthøj JP, Borch L, Hartling U, Schmidt LS, Rytter MJH, Rasmussen AH, Damkjær M, Lemvik G, Petersen JJH, Søndergaard MJ, Thaarup J, Kristensen K, Jensen LH, Hansen LH, Lawaetz MC, Gottliebsen M, Horsager TH, Zaharov T, Hoffmann TU, Nygaard T, Justesen US, Stensballe LG, Vissing NH, Blanche P, Schmiegelow K, Nygaard U. Nielsen AB, et al. Among authors: schmidt ls. Lancet Child Adolesc Health. 2024 Sep;8(9):625-635. doi: 10.1016/S2352-4642(24)00133-0. Epub 2024 Jul 15. Lancet Child Adolesc Health. 2024. PMID: 39025092 Clinical Trial.
198 results