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The life span determinant p66Shc localizes to mitochondria where it associates with mitochondrial heat shock protein 70 and regulates trans-membrane potential.
Orsini F, Migliaccio E, Moroni M, Contursi C, Raker VA, Piccini D, Martin-Padura I, Pelliccia G, Trinei M, Bono M, Puri C, Tacchetti C, Ferrini M, Mannucci R, Nicoletti I, Lanfrancone L, Giorgio M, Pelicci PG. Orsini F, et al. Among authors: pelicci pg. J Biol Chem. 2004 Jun 11;279(24):25689-95. doi: 10.1074/jbc.M401844200. Epub 2004 Apr 12. J Biol Chem. 2004. PMID: 15078873 Free article.
Cancer genetics.
Lanfrancone L, Pelicci G, Pelicci PG. Lanfrancone L, et al. Among authors: pelicci pg, pelicci g. Curr Opin Genet Dev. 1994 Feb;4(1):109-19. doi: 10.1016/0959-437x(94)90099-x. Curr Opin Genet Dev. 1994. PMID: 7910768 Review.
Not all Shc's roads lead to Ras.
Bonfini L, Migliaccio E, Pelicci G, Lanfrancone L, Pelicci PG. Bonfini L, et al. Among authors: pelicci pg, pelicci g. Trends Biochem Sci. 1996 Jul;21(7):257-61. Trends Biochem Sci. 1996. PMID: 8755247 Review.
547 results