Bohlen P - Search Results

1

VEGF-A promotes tissue repair-associated lymphatic vessel formation via VEGFR-2 and the alpha1beta1 and alpha2beta1 integrins.

Hong YK, Lange-Asschenfeldt B, Velasco P, Hirakawa S, Kunstfeld R, Brown LF, Bohlen P, Senger DR, Detmar M. Hong YK, et al. Among authors: bohlen p. FASEB J. 2004 Jul;18(10):1111-3. doi: 10.1096/fj.03-1179fje. Epub 2004 May 7. FASEB J. 2004. PMID: 15132990

2

Induction of cutaneous delayed-type hypersensitivity reactions in VEGF-A transgenic mice results in chronic skin inflammation associated with persistent lymphatic hyperplasia.

Kunstfeld R, Hirakawa S, Hong YK, Schacht V, Lange-Asschenfeldt B, Velasco P, Lin C, Fiebiger E, Wei X, Wu Y, Hicklin D, Bohlen P, Detmar M. Kunstfeld R, et al. Among authors: bohlen p. Blood. 2004 Aug 15;104(4):1048-57. doi: 10.1182/blood-2003-08-2964. Epub 2004 Apr 20. Blood. 2004. PMID: 15100155 Free article.

3

Vascular endothelial growth factor receptor-2-blocking antibody potentiates radiation-induced long-term control of human tumor xenografts.

Kozin SV, Boucher Y, Hicklin DJ, Bohlen P, Jain RK, Suit HD. Kozin SV, et al. Among authors: bohlen p. Cancer Res. 2001 Jan 1;61(1):39-44. Cancer Res. 2001. PMID: 11196192

4

Complete inhibition of vascular endothelial growth factor (VEGF) activities with a bifunctional diabody directed against both VEGF kinase receptors, fms-like tyrosine kinase receptor and kinase insert domain-containing receptor.

Lu D, Jimenez X, Zhang H, Wu Y, Bohlen P, Witte L, Zhu Z. Lu D, et al. Among authors: bohlen p. Cancer Res. 2001 Oct 1;61(19):7002-8. Cancer Res. 2001. PMID: 11585724

5

Monoclonal antibodies targeting the VEGF receptor-2 (Flk1/KDR) as an anti-angiogenic therapeutic strategy.

Witte L, Hicklin DJ, Zhu Z, Pytowski B, Kotanides H, Rockwell P, Böhlen P. Witte L, et al. Among authors: bohlen p. Cancer Metastasis Rev. 1998 Jun;17(2):155-61. doi: 10.1023/a:1006094117427. Cancer Metastasis Rev. 1998. PMID: 9770111 Review.

6

Differences in therapeutic indexes of combination metronomic chemotherapy and an anti-VEGFR-2 antibody in multidrug-resistant human breast cancer xenografts.

Klement G, Huang P, Mayer B, Green SK, Man S, Bohlen P, Hicklin D, Kerbel RS. Klement G, et al. Among authors: bohlen p. Clin Cancer Res. 2002 Jan;8(1):221-32. Clin Cancer Res. 2002. PMID: 11801563

7

Selection of high affinity human neutralizing antibodies to VEGFR2 from a large antibody phage display library for antiangiogenesis therapy.

Lu D, Jimenez X, Zhang H, Bohlen P, Witte L, Zhu Z. Lu D, et al. Among authors: bohlen p. Int J Cancer. 2002 Jan 20;97(3):393-9. doi: 10.1002/ijc.1634. Int J Cancer. 2002. PMID: 11774295

8

Acquired resistance to the antitumor effect of epidermal growth factor receptor-blocking antibodies in vivo: a role for altered tumor angiogenesis.

Viloria-Petit A, Crombet T, Jothy S, Hicklin D, Bohlen P, Schlaeppi JM, Rak J, Kerbel RS. Viloria-Petit A, et al. Among authors: bohlen p. Cancer Res. 2001 Jul 1;61(13):5090-101. Cancer Res. 2001. PMID: 11431346

9

Inhibition of both the autocrine and the paracrine growth of human leukemia with a fully human antibody directed against vascular endothelial growth factor receptor 2.

Zhang H, Li Y, Li H, Bassi R, Jimenez X, Witte L, Bohlen P, Hicklin D, Zhu Z. Zhang H, et al. Among authors: bohlen p. Leuk Lymphoma. 2004 Sep;45(9):1887-97. doi: 10.1080/10428190410001712225. Leuk Lymphoma. 2004. PMID: 15223651

10

Inhibition of both paracrine and autocrine VEGF/ VEGFR-2 signaling pathways is essential to induce long-term remission of xenotransplanted human leukemias.

Dias S, Hattori K, Heissig B, Zhu Z, Wu Y, Witte L, Hicklin DJ, Tateno M, Bohlen P, Moore MA, Rafii S. Dias S, et al. Among authors: bohlen p. Proc Natl Acad Sci U S A. 2001 Sep 11;98(19):10857-62. doi: 10.1073/pnas.191117498. Proc Natl Acad Sci U S A. 2001. PMID: 11553814 Free PMC article.

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