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Mechanisms of hepatic very low density lipoprotein overproduction in insulin resistance. Evidence for enhanced lipoprotein assembly, reduced intracellular ApoB degradation, and increased microsomal triglyceride transfer protein in a fructose-fed hamster model.
Taghibiglou C, Carpentier A, Van Iderstine SC, Chen B, Rudy D, Aiton A, Lewis GF, Adeli K. Taghibiglou C, et al. Among authors: adeli k. J Biol Chem. 2000 Mar 24;275(12):8416-25. doi: 10.1074/jbc.275.12.8416. J Biol Chem. 2000. PMID: 10722675 Free article.
Hepatic very low density lipoprotein-ApoB overproduction is associated with attenuated hepatic insulin signaling and overexpression of protein-tyrosine phosphatase 1B in a fructose-fed hamster model of insulin resistance.
Taghibiglou C, Rashid-Kolvear F, Van Iderstine SC, Le-Tien H, Fantus IG, Lewis GF, Adeli K. Taghibiglou C, et al. Among authors: adeli k. J Biol Chem. 2002 Jan 4;277(1):793-803. doi: 10.1074/jbc.M106737200. Epub 2001 Oct 11. J Biol Chem. 2002. PMID: 11598116 Free article.
Treatment with atorvastatin ameliorates hepatic very-low-density lipoprotein overproduction in an animal model of insulin resistance, the fructose-fed Syrian golden hamster: evidence that reduced hypertriglyceridemia is accompanied by improved hepatic insulin sensitivity.
Mangaloglu L, Cheung RC, Van Iderstine SC, Taghibiglou C, Pontrelli L, Adeli K. Mangaloglu L, et al. Among authors: adeli k. Metabolism. 2002 Apr;51(4):409-18. doi: 10.1053/meta.2002.30954. Metabolism. 2002. PMID: 11912545
Ameliorated hepatic insulin resistance is associated with normalization of microsomal triglyceride transfer protein expression and reduction in very low density lipoprotein assembly and secretion in the fructose-fed hamster.
Carpentier A, Taghibiglou C, Leung N, Szeto L, Van Iderstine SC, Uffelman KD, Buckingham R, Adeli K, Lewis GF. Carpentier A, et al. Among authors: adeli k. J Biol Chem. 2002 Aug 9;277(32):28795-802. doi: 10.1074/jbc.M204568200. Epub 2002 Jun 4. J Biol Chem. 2002. PMID: 12048212 Free article.
399 results