Brooks AG - Search Results

1

Crystal structure of the human T cell receptor CD3 epsilon gamma heterodimer complexed to the therapeutic mAb OKT3.

Kjer-Nielsen L, Dunstone MA, Kostenko L, Ely LK, Beddoe T, Mifsud NA, Purcell AW, Brooks AG, McCluskey J, Rossjohn J. Kjer-Nielsen L, et al. Among authors: brooks ag. Proc Natl Acad Sci U S A. 2004 May 18;101(20):7675-80. doi: 10.1073/pnas.0402295101. Epub 2004 May 10. Proc Natl Acad Sci U S A. 2004. PMID: 15136729 Free PMC article.

2

Class II-restricted presentation of an endogenously derived immunodominant T-cell determinant of hen egg lysozyme.

Brooks A, Hartley S, Kjer-Nielsen L, Perera J, Goodnow CC, Basten A, McCluskey J. Brooks A, et al. Proc Natl Acad Sci U S A. 1991 Apr 15;88(8):3290-4. doi: 10.1073/pnas.88.8.3290. Proc Natl Acad Sci U S A. 1991. PMID: 1707537 Free PMC article.

3

Antigen presentation and assembly by mouse I-Ak class II molecules in human APC containing deleted or mutated HLA DM genes.

Brooks AG, Campbell PL, Reynolds P, Gautam AM, McCluskey J. Brooks AG, et al. J Immunol. 1994 Dec 15;153(12):5382-92. J Immunol. 1994. PMID: 7989744

4

Class II-restricted presentation of a hen egg lysozyme determinant derived from endogenous antigen sequestered in the cytoplasm or endoplasmic reticulum of the antigen presenting cells.

Brooks AG, McCluskey J. Brooks AG, et al. J Immunol. 1993 May 1;150(9):3690-7. J Immunol. 1993. PMID: 8473726

5

Identification of a dominant self-ligand bound to three HLA B44 alleles and the preliminary crystallographic analysis of recombinant forms of each complex.

Macdonald W, Williams DS, Clements CS, Gorman JJ, Kjer-Nielsen L, Brooks AG, McCluskey J, Rossjohn J, Purcell AW. Macdonald W, et al. Among authors: brooks ag. FEBS Lett. 2002 Sep 11;527(1-3):27-32. doi: 10.1016/s0014-5793(02)03149-6. FEBS Lett. 2002. PMID: 12220628 Free article.

6

The structure of HLA-B8 complexed to an immunodominant viral determinant: peptide-induced conformational changes and a mode of MHC class I dimerization.

Kjer-Nielsen L, Clements CS, Brooks AG, Purcell AW, Fontes MR, McCluskey J, Rossjohn J. Kjer-Nielsen L, et al. Among authors: brooks ag. J Immunol. 2002 Nov 1;169(9):5153-60. doi: 10.4049/jimmunol.169.9.5153. J Immunol. 2002. PMID: 12391232

7

The 1.5 A crystal structure of a highly selected antiviral T cell receptor provides evidence for a structural basis of immunodominance.

Kjer-Nielsen L, Clements CS, Brooks AG, Purcell AW, McCluskey J, Rossjohn J. Kjer-Nielsen L, et al. Among authors: brooks ag. Structure. 2002 Nov;10(11):1521-32. doi: 10.1016/s0969-2126(02)00878-x. Structure. 2002. PMID: 12429093 Free article.

8

The production, purification and crystallization of a soluble heterodimeric form of a highly selected T-cell receptor in its unliganded and liganded state.

Clements CS, Kjer-Nielsen L, MacDonald WA, Brooks AG, Purcell AW, McCluskey J, Rossjohn J. Clements CS, et al. Among authors: brooks ag. Acta Crystallogr D Biol Crystallogr. 2002 Dec;58(Pt 12):2131-4. doi: 10.1107/s0907444902015482. Epub 2002 Nov 23. Acta Crystallogr D Biol Crystallogr. 2002. PMID: 12454477

9

A structural basis for the selection of dominant alphabeta T cell receptors in antiviral immunity.

Kjer-Nielsen L, Clements CS, Purcell AW, Brooks AG, Whisstock JC, Burrows SR, McCluskey J, Rossjohn J. Kjer-Nielsen L, et al. Among authors: brooks ag. Immunity. 2003 Jan;18(1):53-64. doi: 10.1016/s1074-7613(02)00513-7. Immunity. 2003. PMID: 12530975 Free article.

10

A naturally selected dimorphism within the HLA-B44 supertype alters class I structure, peptide repertoire, and T cell recognition.

Macdonald WA, Purcell AW, Mifsud NA, Ely LK, Williams DS, Chang L, Gorman JJ, Clements CS, Kjer-Nielsen L, Koelle DM, Burrows SR, Tait BD, Holdsworth R, Brooks AG, Lovrecz GO, Lu L, Rossjohn J, McCluskey J. Macdonald WA, et al. Among authors: brooks ag. J Exp Med. 2003 Sep 1;198(5):679-91. doi: 10.1084/jem.20030066. Epub 2003 Aug 25. J Exp Med. 2003. PMID: 12939341 Free PMC article.

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