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A novel approach to specific allergy treatment: the recombinant fusion protein of a bacterial cell surface (S-layer) protein and the major birch pollen allergen Bet v 1 (rSbsC-Bet v 1) combines reduced allergenicity with immunomodulating capacity.
Bohle B, Breitwieser A, Zwölfer B, Jahn-Schmid B, Sára M, Sleytr UB, Ebner C. Bohle B, et al. Among authors: breitwieser a. J Immunol. 2004 Jun 1;172(11):6642-8. doi: 10.4049/jimmunol.172.11.6642. J Immunol. 2004. PMID: 15153479
Applications of S-layers.
Sleytr UB, Bayley H, Sára M, Breitwieser A, Küpcü S, Mader C, Weigert S, Unger FM, Messner P, Jahn-Schmid B, Schuster B, Pum D, Douglas K, Clark NA, Moore JT, Winningham TA, Levy S, Frithsen I, Pankovc J, Beale P, Gillis HP, Choutov DA, Martin KP. Sleytr UB, et al. Among authors: breitwieser a. FEMS Microbiol Rev. 1997 Jun;20(1-2):151-75. doi: 10.1111/j.1574-6976.1997.tb00306.x. FEMS Microbiol Rev. 1997. PMID: 9276930 Free article. Review.
Molecular characterization of the S-layer gene, sbpA, of Bacillus sphaericus CCM 2177 and production of a functional S-layer fusion protein with the ability to recrystallize in a defined orientation while presenting the fused allergen.
Ilk N, Völlenkle C, Egelseer EM, Breitwieser A, Sleytr UB, Sára M. Ilk N, et al. Among authors: breitwieser a. Appl Environ Microbiol. 2002 Jul;68(7):3251-60. doi: 10.1128/AEM.68.7.3251-3260.2002. Appl Environ Microbiol. 2002. PMID: 12089001 Free PMC article.
15 results