McMahon LM - Search Results

1

mTOR inhibition reverses Akt-dependent prostate intraepithelial neoplasia through regulation of apoptotic and HIF-1-dependent pathways.

Majumder PK, Febbo PG, Bikoff R, Berger R, Xue Q, McMahon LM, Manola J, Brugarolas J, McDonnell TJ, Golub TR, Loda M, Lane HA, Sellers WR. Majumder PK, et al. Among authors: mcmahon lm. Nat Med. 2004 Jun;10(6):594-601. doi: 10.1038/nm1052. Epub 2004 May 23. Nat Med. 2004. PMID: 15156201

2

Comparative pharmacokinetics of RAD001 (everolimus) in normal and tumor-bearing rodents.

O'Reilly T, McSheehy PM, Kawai R, Kretz O, McMahon L, Brueggen J, Bruelisauer A, Gschwind HP, Allegrini PR, Lane HA. O'Reilly T, et al. Cancer Chemother Pharmacol. 2010 Mar;65(4):625-39. doi: 10.1007/s00280-009-1068-8. Epub 2009 Sep 27. Cancer Chemother Pharmacol. 2010. PMID: 19784839

3

Clinical development of an everolimus pediatric formulation: relative bioavailability, food effect, and steady-state pharmacokinetics.

Kovarik JM, Noe A, Berthier S, McMahon L, Langholff WK, Marion AS, Hoyer PF, Ettenger R, Rordorf C. Kovarik JM, et al. J Clin Pharmacol. 2003 Feb;43(2):141-7. doi: 10.1177/0091270002239822. J Clin Pharmacol. 2003. PMID: 12616666 Clinical Trial.

4

Population pharmacokinetics of everolimus in de novo renal transplant patients: impact of ethnicity and comedications.

Kovarik JM, Hsu CH, McMahon L, Berthier S, Rordorf C. Kovarik JM, et al. Clin Pharmacol Ther. 2001 Sep;70(3):247-54. doi: 10.1067/mcp.2001.118022. Clin Pharmacol Ther. 2001. PMID: 11557912 Clinical Trial.

5

Pharmacokinetics of an everolimus-cyclosporine immunosuppressive regimen over the first 6 months after kidney transplantation.

Kovarik JM, Kaplan B, Silva HT, Kahan BD, Dantal J, McMahon L, Berthier S, Hsu CH, Rordorf C. Kovarik JM, et al. Am J Transplant. 2003 May;3(5):606-13. doi: 10.1034/j.1600-6143.2003.00107.x. Am J Transplant. 2003. PMID: 12752317 Free article. Clinical Trial.

6

High-throughput analysis of everolimus (RAD001) and cyclosporin A (CsA) in whole blood by liquid chromatography/mass spectrometry using a semi-automated 96-well solid-phase extraction system.

McMahon LM, Luo S, Hayes M, Tse FL. McMahon LM, et al. Rapid Commun Mass Spectrom. 2000;14(21):1965-71. doi: 10.1002/1097-0231(20001115)14:21<1965::AID-RCM118>3.0.CO;2-0. Rapid Commun Mass Spectrom. 2000. PMID: 11085405

7

High-throughput semi-automated 96-well liquid/liquid extraction and liquid chromatography/mass spectrometric analysis of everolimus (RAD 001) and cyclosporin a (CsA) in whole blood.

Brignol N, McMahon LM, Luo S, Tse FL. Brignol N, et al. Among authors: mcmahon lm. Rapid Commun Mass Spectrom. 2001;15(12):898-907. doi: 10.1002/rcm.323. Rapid Commun Mass Spectrom. 2001. PMID: 11400194

8

Single-dose pharmacokinetics and tolerability of everolimus in stable pediatric renal transplant patients.

Van Damme-Lombaerts R, Webb NA, Hoyer PF, Mahan J, Lemire J, Ettenger R, McMahon L, Cambon N, Boger R, Kovarik JM; Everolimus Study Group. Van Damme-Lombaerts R, et al. Pediatr Transplant. 2002 Apr;6(2):147-52. doi: 10.1034/j.1399-3046.2002.01070.x. Pediatr Transplant. 2002. PMID: 12000472 Clinical Trial.

9

Administration diluents differentiate Neoral from a generic cyclosporine oral solution.

Kovarik JM, Barilla D, McMahon L, Wang Y, Kisicki J, Schmouder R. Kovarik JM, et al. Clin Transplant. 2002 Aug;16(4):306-9. doi: 10.1034/j.1399-0012.2002.02011.x. Clin Transplant. 2002. PMID: 12099989 Clinical Trial.

10

High-throughput approaches to the quantitative analysis of ketoconazole, a potent inhibitor of cytochrome P450 3A4, in human plasma.

Ramos L, Brignol N, Bakhtiar R, Ray T, Mc Mahon LM, Tse FL. Ramos L, et al. Rapid Commun Mass Spectrom. 2000;14(23):2282-93. doi: 10.1002/1097-0231(20001215)14:23<2282::AID-RCM164>3.0.CO;2-V. Rapid Commun Mass Spectrom. 2000. PMID: 11114039

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