Baillie TA - Search Results

1

Effect of quinidine on the 10-hydroxylation of R-warfarin: species differences and clearance projection.

Chen Q, Tan E, Strauss JR, Zhang Z, Fenyk-Melody JE, Booth-Genthe C, Rushmore TH, Stearns RA, Evans DC, Baillie TA, Tang W. Chen Q, et al. Among authors: baillie ta. J Pharmacol Exp Ther. 2004 Oct;311(1):307-14. doi: 10.1124/jpet.104.069955. Epub 2004 May 26. J Pharmacol Exp Ther. 2004. PMID: 15163679

2

Extrapolation of diclofenac clearance from in vitro microsomal metabolism data: role of acyl glucuronidation and sequential oxidative metabolism of the acyl glucuronide.

Kumar S, Samuel K, Subramanian R, Braun MP, Stearns RA, Chiu SH, Evans DC, Baillie TA. Kumar S, et al. Among authors: baillie ta. J Pharmacol Exp Ther. 2002 Dec;303(3):969-78. doi: 10.1124/jpet.102.038992. J Pharmacol Exp Ther. 2002. PMID: 12438516

3

Interaction of diclofenac and quinidine in monkeys: stimulation of diclofenac metabolism.

Tang W, Stearns RA, Kwei GY, Iliff SA, Miller RR, Egan MA, Yu NX, Dean DC, Kumar S, Shou M, Lin JH, Baillie TA. Tang W, et al. Among authors: baillie ta. J Pharmacol Exp Ther. 1999 Dec;291(3):1068-74. J Pharmacol Exp Ther. 1999. PMID: 10565826

4

In vitro stimulation of warfarin metabolism by quinidine: increases in the formation of 4'- and 10-hydroxywarfarin.

Ngui JS, Chen Q, Shou M, Wang RW, Stearns RA, Baillie TA, Tang W. Ngui JS, et al. Among authors: baillie ta. Drug Metab Dispos. 2001 Jun;29(6):877-86. Drug Metab Dispos. 2001. PMID: 11353757

5

Influence of different recombinant systems on the cooperativity exhibited by cytochrome P4503A4.

Zhang Z, Li Y, Shou M, Zhang Y, Ngui JS, Stearns RA, Evans DC, Baillie TA, Tang W. Zhang Z, et al. Among authors: baillie ta. Xenobiotica. 2004 May;34(5):473-86. doi: 10.1080/00498250410001691271. Xenobiotica. 2004. PMID: 15370963

6

Evidence for the bioactivation of zomepirac and tolmetin by an oxidative pathway: identification of glutathione adducts in vitro in human liver microsomes and in vivo in rats.

Chen Q, Doss GA, Tung EC, Liu W, Tang YS, Braun MP, Didolkar V, Strauss JR, Wang RW, Stearns RA, Evans DC, Baillie TA, Tang W. Chen Q, et al. Among authors: baillie ta. Drug Metab Dispos. 2006 Jan;34(1):145-51. doi: 10.1124/dmd.105.004341. Epub 2005 Oct 26. Drug Metab Dispos. 2006. PMID: 16251255

7

In vitro metabolic activation of lumiracoxib in rat and human liver preparations.

Li Y, Slatter JG, Zhang Z, Li Y, Doss GA, Braun MP, Stearns RA, Dean DC, Baillie TA, Tang W. Li Y, et al. Among authors: baillie ta. Drug Metab Dispos. 2008 Feb;36(2):469-73. doi: 10.1124/dmd.107.019018. Epub 2007 Nov 12. Drug Metab Dispos. 2008. PMID: 17998295

8

Cytochrome P450 3A4-mediated oxidative conversion of a cyano to an amide group in the metabolism of pinacidil.

Zhang Z, Li Y, Stearns RA, Ortiz De Montellano PR, Baillie TA, Tang W. Zhang Z, et al. Among authors: baillie ta. Biochemistry. 2002 Feb 26;41(8):2712-8. doi: 10.1021/bi0119971. Biochemistry. 2002. PMID: 11851418

9

Metabolism of a thiazole benzenesulfonamide derivative, a potent and elective agonist of the human beta3-adrenergic receptor, in rats: identification of a novel isethionic acid conjugate.

Tang W, Stearns RA, Miller RR, Ngui JS, Mathvink RJ, Weber AE, Kwei GY, Strauss JR, Keohane CA, Doss GA, Chiu SH, Baillie TA. Tang W, et al. Among authors: baillie ta. Drug Metab Dispos. 2002 Jul;30(7):778-87. doi: 10.1124/dmd.30.7.778. Drug Metab Dispos. 2002. PMID: 12065436

10

Cytochrome P450 3A4-mediated bioactivation of raloxifene: irreversible enzyme inhibition and thiol adduct formation.

Chen Q, Ngui JS, Doss GA, Wang RW, Cai X, DiNinno FP, Blizzard TA, Hammond ML, Stearns RA, Evans DC, Baillie TA, Tang W. Chen Q, et al. Among authors: baillie ta. Chem Res Toxicol. 2002 Jul;15(7):907-14. doi: 10.1021/tx0200109. Chem Res Toxicol. 2002. PMID: 12119000

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