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A Thr357 to Ser polymorphism in homozygous and compound heterozygous subjects causes absent or reduced P2X7 function and impairs ATP-induced mycobacterial killing by macrophages.
Shemon AN, Sluyter R, Fernando SL, Clarke AL, Dao-Ung LP, Skarratt KK, Saunders BM, Tan KS, Gu BJ, Fuller SJ, Britton WJ, Petrou S, Wiley JS. Shemon AN, et al. Among authors: skarratt kk. J Biol Chem. 2006 Jan 27;281(4):2079-86. doi: 10.1074/jbc.M507816200. Epub 2005 Nov 1. J Biol Chem. 2006. PMID: 16263709 Free article.
Genetics of the P2X7 receptor and human disease.
Fuller SJ, Stokes L, Skarratt KK, Gu BJ, Wiley JS. Fuller SJ, et al. Among authors: skarratt kk. Purinergic Signal. 2009 Jun;5(2):257-62. doi: 10.1007/s11302-009-9136-4. Epub 2009 Mar 25. Purinergic Signal. 2009. PMID: 19319666 Free PMC article.
Identification of the promoter region of the P2RX4 gene.
Gu BJ, Sun C, Valova VA, Skarratt KK, Wiley JS. Gu BJ, et al. Among authors: skarratt kk. Mol Biol Rep. 2010 Oct;37(7):3369-76. doi: 10.1007/s11033-009-9924-5. Epub 2009 Dec 2. Mol Biol Rep. 2010. PMID: 19953327
34 results