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Page 1
Engineering of an artificial glycosylation pathway blocked in core oligosaccharide assembly in the yeast Pichia pastoris: production of complex humanized glycoproteins with terminal galactose.
Bobrowicz P, Davidson RC, Li H, Potgieter TI, Nett JH, Hamilton SR, Stadheim TA, Miele RG, Bobrowicz B, Mitchell T, Rausch S, Renfer E, Wildt S. Bobrowicz P, et al. Among authors: stadheim ta. Glycobiology. 2004 Sep;14(9):757-66. doi: 10.1093/glycob/cwh104. Epub 2004 Jun 9. Glycobiology. 2004. PMID: 15190003
Production of complex human glycoproteins in yeast.
Hamilton SR, Bobrowicz P, Bobrowicz B, Davidson RC, Li H, Mitchell T, Nett JH, Rausch S, Stadheim TA, Wischnewski H, Wildt S, Gerngross TU. Hamilton SR, et al. Among authors: stadheim ta. Science. 2003 Aug 29;301(5637):1244-6. doi: 10.1126/science.1088166. Science. 2003. PMID: 12947202
Optimization of humanized IgGs in glycoengineered Pichia pastoris.
Li H, Sethuraman N, Stadheim TA, Zha D, Prinz B, Ballew N, Bobrowicz P, Choi BK, Cook WJ, Cukan M, Houston-Cummings NR, Davidson R, Gong B, Hamilton SR, Hoopes JP, Jiang Y, Kim N, Mansfield R, Nett JH, Rios S, Strawbridge R, Wildt S, Gerngross TU. Li H, et al. Among authors: stadheim ta. Nat Biotechnol. 2006 Feb;24(2):210-5. doi: 10.1038/nbt1178. Epub 2006 Jan 22. Nat Biotechnol. 2006. PMID: 16429149
Humanization of yeast to produce complex terminally sialylated glycoproteins.
Hamilton SR, Davidson RC, Sethuraman N, Nett JH, Jiang Y, Rios S, Bobrowicz P, Stadheim TA, Li H, Choi BK, Hopkins D, Wischnewski H, Roser J, Mitchell T, Strawbridge RR, Hoopes J, Wildt S, Gerngross TU. Hamilton SR, et al. Among authors: stadheim ta. Science. 2006 Sep 8;313(5792):1441-3. doi: 10.1126/science.1130256. Science. 2006. PMID: 16960007
Elimination of β-mannose glycan structures in Pichia pastoris.
Hopkins D, Gomathinayagam S, Rittenhour AM, Du M, Hoyt E, Karaveg K, Mitchell T, Nett JH, Sharkey NJ, Stadheim TA, Li H, Hamilton SR. Hopkins D, et al. Among authors: stadheim ta. Glycobiology. 2011 Dec;21(12):1616-26. doi: 10.1093/glycob/cwr108. Epub 2011 Aug 12. Glycobiology. 2011. PMID: 21840970
Optimization of erythropoietin production with controlled glycosylation-PEGylated erythropoietin produced in glycoengineered Pichia pastoris.
Nett JH, Gomathinayagam S, Hamilton SR, Gong B, Davidson RC, Du M, Hopkins D, Mitchell T, Mallem MR, Nylen A, Shaikh SS, Sharkey N, Barnard GC, Copeland V, Liu L, Evers R, Li Y, Gray PM, Lingham RB, Visco D, Forrest G, DeMartino J, Linden T, Potgieter TI, Wildt S, Stadheim TA, d'Anjou M, Li H, Sethuraman N. Nett JH, et al. Among authors: stadheim ta. J Biotechnol. 2012 Jan;157(1):198-206. doi: 10.1016/j.jbiotec.2011.11.002. Epub 2011 Nov 9. J Biotechnol. 2012. PMID: 22100268
Production of sialylated O-linked glycans in Pichia pastoris.
Hamilton SR, Cook WJ, Gomathinayagam S, Burnina I, Bukowski J, Hopkins D, Schwartz S, Du M, Sharkey NJ, Bobrowicz P, Wildt S, Li H, Stadheim TA, Nett JH. Hamilton SR, et al. Among authors: stadheim ta. Glycobiology. 2013 Oct;23(10):1192-203. doi: 10.1093/glycob/cwt056. Epub 2013 Jul 26. Glycobiology. 2013. PMID: 23893788
42 results