Irwin RD - Search Results

1

Application of toxicogenomics to toxicology: basic concepts in the analysis of microarray data.

Irwin RD, Boorman GA, Cunningham ML, Heinloth AN, Malarkey DE, Paules RS. Irwin RD, et al. Toxicol Pathol. 2004 Mar-Apr;32 Suppl 1:72-83. doi: 10.1080/01926230490424752. Toxicol Pathol. 2004. PMID: 15209406 Review.

2

Variation in the hepatic gene expression in individual male Fischer rats.

Boorman GA, Irwin RD, Vallant MK, Gerken DK, Lobenhofer EK, Hejtmancik MR, Hurban P, Brys AM, Travlos GS, Parker JS, Portier CJ. Boorman GA, et al. Among authors: irwin rd. Toxicol Pathol. 2005;33(1):102-10. doi: 10.1080/01926230590522211. Toxicol Pathol. 2005. PMID: 15805061

3

Transcriptional profiling of the left and median liver lobes of male f344/n rats following exposure to acetaminophen.

Irwin RD, Parker JS, Lobenhofer EK, Burka LT, Blackshear PE, Vallant MK, Lebetkin EH, Gerken DF, Boorman GA. Irwin RD, et al. Toxicol Pathol. 2005;33(1):111-7. doi: 10.1080/01926230590522257. Toxicol Pathol. 2005. PMID: 15805062

4

Hepatic transcript levels for genes coding for enzymes associated with xenobiotic metabolism are altered with age.

Mori K, Blackshear PE, Lobenhofer EK, Parker JS, Orzech DP, Roycroft JH, Walker KL, Johnson KA, Marsh TA, Irwin RD, Boorman GA. Mori K, et al. Among authors: irwin rd. Toxicol Pathol. 2007 Feb;35(2):242-51. doi: 10.1080/01926230601156286. Toxicol Pathol. 2007. PMID: 17366318

5

Systems toxicology and the Chemical Effects in Biological Systems (CEBS) knowledge base.

Waters M, Boorman G, Bushel P, Cunningham M, Irwin R, Merrick A, Olden K, Paules R, Selkirk J, Stasiewicz S, Weis B, Van Houten B, Walker N, Tennant R. Waters M, et al. EHP Toxicogenomics. 2003 Jan;111(1T):15-28. EHP Toxicogenomics. 2003. PMID: 12735106

6

Gene expression profiling of rat livers reveals indicators of potential adverse effects.

Heinloth AN, Irwin RD, Boorman GA, Nettesheim P, Fannin RD, Sieber SO, Snell ML, Tucker CJ, Li L, Travlos GS, Vansant G, Blackshear PE, Tennant RW, Cunningham ML, Paules RS. Heinloth AN, et al. Among authors: irwin rd. Toxicol Sci. 2004 Jul;80(1):193-202. doi: 10.1093/toxsci/kfh145. Epub 2004 Apr 14. Toxicol Sci. 2004. PMID: 15084756

7

Hepatic gene expression changes throughout the day in the Fischer rat: implications for toxicogenomic experiments.

Boorman GA, Blackshear PE, Parker JS, Lobenhofer EK, Malarkey DE, Vallant MK, Gerken DK, Irwin RD. Boorman GA, et al. Among authors: irwin rd. Toxicol Sci. 2005 Jul;86(1):185-93. doi: 10.1093/toxsci/kfi166. Epub 2005 Apr 6. Toxicol Sci. 2005. PMID: 15814895

8

Gene interaction network analysis suggests differences between high and low doses of acetaminophen.

Toyoshiba H, Sone H, Yamanaka T, Parham FM, Irwin RD, Boorman GA, Portier CJ. Toyoshiba H, et al. Among authors: irwin rd. Toxicol Appl Pharmacol. 2006 Sep 15;215(3):306-16. doi: 10.1016/j.taap.2006.03.009. Epub 2006 May 15. Toxicol Appl Pharmacol. 2006. PMID: 16701773

9

Gene set enrichment analysis for non-monotone association and multiple experimental categories.

Lin R, Dai S, Irwin RD, Heinloth AN, Boorman GA, Li L. Lin R, et al. Among authors: irwin rd. BMC Bioinformatics. 2008 Nov 14;9:481. doi: 10.1186/1471-2105-9-481. BMC Bioinformatics. 2008. PMID: 19014579 Free PMC article.

10

Predicting the hepatocarcinogenic potential of alkenylbenzene flavoring agents using toxicogenomics and machine learning.

Auerbach SS, Shah RR, Mav D, Smith CS, Walker NJ, Vallant MK, Boorman GA, Irwin RD. Auerbach SS, et al. Among authors: irwin rd. Toxicol Appl Pharmacol. 2010 Mar 15;243(3):300-14. doi: 10.1016/j.taap.2009.11.021. Epub 2009 Dec 11. Toxicol Appl Pharmacol. 2010. PMID: 20004213

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