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Furin-cleaved proprotein convertase subtilisin/kexin type 9 (PCSK9) is active and modulates low density lipoprotein receptor and serum cholesterol levels.
Lipari MT, Li W, Moran P, Kong-Beltran M, Sai T, Lai J, Lin SJ, Kolumam G, Zavala-Solorio J, Izrael-Tomasevic A, Arnott D, Wang J, Peterson AS, Kirchhofer D. Lipari MT, et al. J Biol Chem. 2012 Dec 21;287(52):43482-91. doi: 10.1074/jbc.M112.380618. Epub 2012 Nov 7. J Biol Chem. 2012. PMID: 23135270 Free PMC article.
Structural insight into distinct mechanisms of protease inhibition by antibodies.
Wu Y, Eigenbrot C, Liang WC, Stawicki S, Shia S, Fan B, Ganesan R, Lipari MT, Kirchhofer D. Wu Y, et al. Among authors: lipari mt. Proc Natl Acad Sci U S A. 2007 Dec 11;104(50):19784-9. doi: 10.1073/pnas.0708251104. Epub 2007 Dec 5. Proc Natl Acad Sci U S A. 2007. PMID: 18077410 Free PMC article.
Structural and functional analysis of HtrA1 and its subdomains.
Eigenbrot C, Ultsch M, Lipari MT, Moran P, Lin SJ, Ganesan R, Quan C, Tom J, Sandoval W, van Lookeren Campagne M, Kirchhofer D. Eigenbrot C, et al. Among authors: lipari mt. Structure. 2012 Jun 6;20(6):1040-50. doi: 10.1016/j.str.2012.03.021. Epub 2012 May 10. Structure. 2012. PMID: 22578544 Free article.
27 results