Inoki K - Search Results

1

Regulation of the TSC pathway by LKB1: evidence of a molecular link between tuberous sclerosis complex and Peutz-Jeghers syndrome.

Corradetti MN, Inoki K, Bardeesy N, DePinho RA, Guan KL. Corradetti MN, et al. Among authors: inoki k. Genes Dev. 2004 Jul 1;18(13):1533-8. doi: 10.1101/gad.1199104. Genes Dev. 2004. PMID: 15231735 Free PMC article.

2

TSC2 is phosphorylated and inhibited by Akt and suppresses mTOR signalling.

Inoki K, Li Y, Zhu T, Wu J, Guan KL. Inoki K, et al. Nat Cell Biol. 2002 Sep;4(9):648-57. doi: 10.1038/ncb839. Nat Cell Biol. 2002. PMID: 12172553

3

Regulation of TSC2 by 14-3-3 binding.

Li Y, Inoki K, Yeung R, Guan KL. Li Y, et al. Among authors: inoki k. J Biol Chem. 2002 Nov 22;277(47):44593-6. doi: 10.1074/jbc.C200510200. Epub 2002 Oct 2. J Biol Chem. 2002. PMID: 12364343 Free article.

4

The p38 and MK2 kinase cascade phosphorylates tuberin, the tuberous sclerosis 2 gene product, and enhances its interaction with 14-3-3.

Li Y, Inoki K, Vacratsis P, Guan KL. Li Y, et al. Among authors: inoki k. J Biol Chem. 2003 Apr 18;278(16):13663-71. doi: 10.1074/jbc.M300862200. Epub 2003 Feb 11. J Biol Chem. 2003. PMID: 12582162 Free article.

5

Rheb GTPase is a direct target of TSC2 GAP activity and regulates mTOR signaling.

Inoki K, Li Y, Xu T, Guan KL. Inoki K, et al. Genes Dev. 2003 Aug 1;17(15):1829-34. doi: 10.1101/gad.1110003. Epub 2003 Jul 17. Genes Dev. 2003. PMID: 12869586 Free PMC article.

6

TSC2 mediates cellular energy response to control cell growth and survival.

Inoki K, Zhu T, Guan KL. Inoki K, et al. Cell. 2003 Nov 26;115(5):577-90. doi: 10.1016/s0092-8674(03)00929-2. Cell. 2003. PMID: 14651849 Free article.

7

TSC2: filling the GAP in the mTOR signaling pathway.

Li Y, Corradetti MN, Inoki K, Guan KL. Li Y, et al. Among authors: inoki k. Trends Biochem Sci. 2004 Jan;29(1):32-8. doi: 10.1016/j.tibs.2003.11.007. Trends Biochem Sci. 2004. PMID: 14729330 Review.

8

Biochemical and functional characterizations of small GTPase Rheb and TSC2 GAP activity.

Li Y, Inoki K, Guan KL. Li Y, et al. Among authors: inoki k. Mol Cell Biol. 2004 Sep;24(18):7965-75. doi: 10.1128/MCB.24.18.7965-7975.2004. Mol Cell Biol. 2004. PMID: 15340059 Free PMC article.

9

Dysregulation of the TSC-mTOR pathway in human disease.

Inoki K, Corradetti MN, Guan KL. Inoki K, et al. Nat Genet. 2005 Jan;37(1):19-24. doi: 10.1038/ng1494. Nat Genet. 2005. PMID: 15624019 Review.

10

The stress-inducted proteins RTP801 and RTP801L are negative regulators of the mammalian target of rapamycin pathway.

Corradetti MN, Inoki K, Guan KL. Corradetti MN, et al. Among authors: inoki k. J Biol Chem. 2005 Mar 18;280(11):9769-72. doi: 10.1074/jbc.C400557200. Epub 2005 Jan 4. J Biol Chem. 2005. PMID: 15632201 Free article.

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