Mehmi I - Search Results

1

Inhibition of fatty acid synthase (FAS) suppresses HER2/neu (erbB-2) oncogene overexpression in cancer cells.

Menendez JA, Vellon L, Mehmi I, Oza BP, Ropero S, Colomer R, Lupu R. Menendez JA, et al. Among authors: mehmi i. Proc Natl Acad Sci U S A. 2004 Jul 20;101(29):10715-20. doi: 10.1073/pnas.0403390101. Epub 2004 Jul 2. Proc Natl Acad Sci U S A. 2004. PMID: 15235125 Free PMC article.

2

Novel signaling molecules implicated in tumor-associated fatty acid synthase-dependent breast cancer cell proliferation and survival: Role of exogenous dietary fatty acids, p53-p21WAF1/CIP1, ERK1/2 MAPK, p27KIP1, BRCA1, and NF-kappaB.

Menendez JA, Mehmi I, Atlas E, Colomer R, Lupu R. Menendez JA, et al. Among authors: mehmi i. Int J Oncol. 2004 Mar;24(3):591-608. Int J Oncol. 2004. PMID: 14767544

3

Inhibition of tumor-associated fatty acid synthase activity antagonizes estradiol- and tamoxifen-induced agonist transactivation of estrogen receptor (ER) in human endometrial adenocarcinoma cells.

Menendez JA, Oza BP, Atlas E, Verma VA, Mehmi I, Lupu R. Menendez JA, et al. Among authors: mehmi i. Oncogene. 2004 Jun 17;23(28):4945-58. doi: 10.1038/sj.onc.1207476. Oncogene. 2004. PMID: 15094777

4

Overexpression and hyperactivity of breast cancer-associated fatty acid synthase (oncogenic antigen-519) is insensitive to normal arachidonic fatty acid-induced suppression in lipogenic tissues but it is selectively inhibited by tumoricidal alpha-linolenic and gamma-linolenic fatty acids: a novel mechanism by which dietary fat can alter mammary tumorigenesis.

Menendez JA, Ropero S, Mehmi I, Atlas E, Colomer R, Lupu R. Menendez JA, et al. Among authors: mehmi i. Int J Oncol. 2004 Jun;24(6):1369-83. Int J Oncol. 2004. PMID: 15138577

5

Pharmacological inhibition of fatty acid synthase (FAS): a novel therapeutic approach for breast cancer chemoprevention through its ability to suppress Her-2/neu (erbB-2) oncogene-induced malignant transformation.

Menendez JA, Mehmi I, Verma VA, Teng PK, Lupu R. Menendez JA, et al. Among authors: mehmi i. Mol Carcinog. 2004 Nov;41(3):164-78. doi: 10.1002/mc.20054. Mol Carcinog. 2004. PMID: 15390078

6

Heregulin-triggered Her-2/neu signaling enhances nuclear accumulation of p21WAF1/CIP1 and protects breast cancer cells from cisplatin-induced genotoxic damage.

Menendez JA, Mehmi I, Lupu R. Menendez JA, et al. Among authors: mehmi i. Int J Oncol. 2005 Mar;26(3):649-59. Int J Oncol. 2005. PMID: 15703820

7

Trastuzumab in combination with heregulin-activated Her-2 (erbB-2) triggers a receptor-enhanced chemosensitivity effect in the absence of Her-2 overexpression.

Menendez JA, Mehmi I, Lupu R. Menendez JA, et al. Among authors: mehmi i. J Clin Oncol. 2006 Aug 10;24(23):3735-46. doi: 10.1200/JCO.2005.04.3489. Epub 2006 Jul 17. J Clin Oncol. 2006. PMID: 16847284

8

The angiogenic factor CYR61 in breast cancer: molecular pathology and therapeutic perspectives.

Menéndez JA, Mehmi I, Griggs DW, Lupu R. Menéndez JA, et al. Among authors: mehmi i. Endocr Relat Cancer. 2003 Jun;10(2):141-52. doi: 10.1677/erc.0.0100141. Endocr Relat Cancer. 2003. PMID: 12790776 Review.

9

A novel CYR61-triggered 'CYR61-alphavbeta3 integrin loop' regulates breast cancer cell survival and chemosensitivity through activation of ERK1/ERK2 MAPK signaling pathway.

Menendez JA, Vellon L, Mehmi I, Teng PK, Griggs DW, Lupu R. Menendez JA, et al. Among authors: mehmi i. Oncogene. 2005 Jan 27;24(5):761-79. doi: 10.1038/sj.onc.1208238. Oncogene. 2005. PMID: 15592521

10

Heregulin is sufficient for the promotion of tumorigenicity and metastasis of breast cancer cells in vivo.

Atlas E, Cardillo M, Mehmi I, Zahedkargaran H, Tang C, Lupu R. Atlas E, et al. Among authors: mehmi i. Mol Cancer Res. 2003 Jan;1(3):165-75. Mol Cancer Res. 2003. PMID: 12556556 Free article.

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