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Page 1
Enhancing linkage analysis of complex disorders: an evaluation of high-density genotyping.
Sawcer SJ, Maranian M, Singlehurst S, Yeo T, Compston A, Daly MJ, De Jager PL, Gabriel S, Hafler DA, Ivinson AJ, Lander ES, Rioux JD, Walsh E, Gregory SG, Schmidt S, Pericak-Vance MA, Barcellos L, Hauser SL, Oksenberg JR, Kenealy SJ, Haines JL. Sawcer SJ, et al. Among authors: lander es. Hum Mol Genet. 2004 Sep 1;13(17):1943-9. doi: 10.1093/hmg/ddh202. Epub 2004 Jul 6. Hum Mol Genet. 2004. PMID: 15238506
PGC-1alpha-responsive genes involved in oxidative phosphorylation are coordinately downregulated in human diabetes.
Mootha VK, Lindgren CM, Eriksson KF, Subramanian A, Sihag S, Lehar J, Puigserver P, Carlsson E, Ridderstråle M, Laurila E, Houstis N, Daly MJ, Patterson N, Mesirov JP, Golub TR, Tamayo P, Spiegelman B, Lander ES, Hirschhorn JN, Altshuler D, Groop LC. Mootha VK, et al. Among authors: lander es. Nat Genet. 2003 Jul;34(3):267-73. doi: 10.1038/ng1180. Nat Genet. 2003. PMID: 12808457
An integrated haplotype map of the human major histocompatibility complex.
Walsh EC, Mather KA, Schaffner SF, Farwell L, Daly MJ, Patterson N, Cullen M, Carrington M, Bugawan TL, Erlich H, Campbell J, Barrett J, Miller K, Thomson G, Lander ES, Rioux JD. Walsh EC, et al. Among authors: lander es. Am J Hum Genet. 2003 Sep;73(3):580-90. doi: 10.1086/378101. Epub 2003 Aug 14. Am J Hum Genet. 2003. PMID: 12920676 Free PMC article.
Assessing the impact of population stratification on genetic association studies.
Freedman ML, Reich D, Penney KL, McDonald GJ, Mignault AA, Patterson N, Gabriel SB, Topol EJ, Smoller JW, Pato CN, Pato MT, Petryshen TL, Kolonel LN, Lander ES, Sklar P, Henderson B, Hirschhorn JN, Altshuler D. Freedman ML, et al. Among authors: lander es. Nat Genet. 2004 Apr;36(4):388-93. doi: 10.1038/ng1333. Epub 2004 Mar 28. Nat Genet. 2004. PMID: 15052270
Genomewide search and association studies in a Finnish celiac disease population: Identification of a novel locus and replication of the HLA and CTLA4 loci.
Rioux JD, Karinen H, Kocher K, McMahon SG, Kärkkäinen P, Janatuinen E, Heikkinen M, Julkunen R, Pihlajamäki J, Naukkarinen A, Kosma VM, Daly MJ, Lander ES, Laakso M. Rioux JD, et al. Among authors: lander es. Am J Med Genet A. 2004 Nov 1;130A(4):345-50. doi: 10.1002/ajmg.a.30072. Am J Med Genet A. 2004. PMID: 15386476
A high-resolution linkage-disequilibrium map of the human major histocompatibility complex and first generation of tag single-nucleotide polymorphisms.
Miretti MM, Walsh EC, Ke X, Delgado M, Griffiths M, Hunt S, Morrison J, Whittaker P, Lander ES, Cardon LR, Bentley DR, Rioux JD, Beck S, Deloukas P. Miretti MM, et al. Among authors: lander es. Am J Hum Genet. 2005 Apr;76(4):634-46. doi: 10.1086/429393. Epub 2005 Mar 1. Am J Hum Genet. 2005. PMID: 15747258 Free PMC article.
A high-density screen for linkage in multiple sclerosis.
Sawcer S, Ban M, Maranian M, Yeo TW, Compston A, Kirby A, Daly MJ, De Jager PL, Walsh E, Lander ES, Rioux JD, Hafler DA, Ivinson A, Rimmler J, Gregory SG, Schmidt S, Pericak-Vance MA, Akesson E, Hillert J, Datta P, Oturai A, Ryder LP, Harbo HF, Spurkland A, Myhr KM, Laaksonen M, Booth D, Heard R, Stewart G, Lincoln R, Barcellos LF, Hauser SL, Oksenberg JR, Kenealy SJ, Haines JL; International Multiple Sclerosis Genetics Consortium. Sawcer S, et al. Among authors: lander es. Am J Hum Genet. 2005 Sep;77(3):454-67. doi: 10.1086/444547. Epub 2005 Jul 29. Am J Hum Genet. 2005. PMID: 16080120 Free PMC article.
The case for selection at CCR5-Delta32.
Sabeti PC, Walsh E, Schaffner SF, Varilly P, Fry B, Hutcheson HB, Cullen M, Mikkelsen TS, Roy J, Patterson N, Cooper R, Reich D, Altshuler D, O'Brien S, Lander ES. Sabeti PC, et al. Among authors: lander es. PLoS Biol. 2005 Nov;3(11):e378. doi: 10.1371/journal.pbio.0030378. Epub 2005 Nov 1. PLoS Biol. 2005. PMID: 16248677 Free PMC article.
Searching for signals of evolutionary selection in 168 genes related to immune function.
Walsh EC, Sabeti P, Hutcheson HB, Fry B, Schaffner SF, de Bakker PI, Varilly P, Palma AA, Roy J, Cooper R, Winkler C, Zeng Y, de The G, Lander ES, O'Brien S, Altshuler D. Walsh EC, et al. Among authors: lander es. Hum Genet. 2006 Mar;119(1-2):92-102. doi: 10.1007/s00439-005-0090-0. Epub 2005 Dec 14. Hum Genet. 2006. PMID: 16362345
A second major histocompatibility complex susceptibility locus for multiple sclerosis.
Yeo TW, De Jager PL, Gregory SG, Barcellos LF, Walton A, Goris A, Fenoglio C, Ban M, Taylor CJ, Goodman RS, Walsh E, Wolfish CS, Horton R, Traherne J, Beck S, Trowsdale J, Caillier SJ, Ivinson AJ, Green T, Pobywajlo S, Lander ES, Pericak-Vance MA, Haines JL, Daly MJ, Oksenberg JR, Hauser SL, Compston A, Hafler DA, Rioux JD, Sawcer S. Yeo TW, et al. Among authors: lander es. Ann Neurol. 2007 Mar;61(3):228-36. doi: 10.1002/ana.21063. Ann Neurol. 2007. PMID: 17252545 Free PMC article.
554 results