Heimberg H - Search Results

1

Metformin-induced stimulation of AMP-activated protein kinase in beta-cells impairs their glucose responsiveness and can lead to apoptosis.

Kefas BA, Cai Y, Kerckhofs K, Ling Z, Martens G, Heimberg H, Pipeleers D, Van de Casteele M. Kefas BA, et al. Among authors: heimberg h. Biochem Pharmacol. 2004 Aug 1;68(3):409-16. doi: 10.1016/j.bcp.2004.04.003. Biochem Pharmacol. 2004. PMID: 15242807

2

Specific expression of Bax-omega in pancreatic beta-cells is down-regulated by cytokines before the onset of apoptosis.

Van de Casteele M, Kefas BA, Ling Z, Heimberg H, Pipeleers DG. Van de Casteele M, et al. Among authors: heimberg h. Endocrinology. 2002 Jan;143(1):320-6. doi: 10.1210/endo.143.1.8574. Endocrinology. 2002. PMID: 11751624

3

Variations in IB1/JIP1 expression regulate susceptibility of beta-cells to cytokine-induced apoptosis irrespective of C-Jun NH2-terminal kinase signaling.

Ling Z, Van de Casteele M, Dong J, Heimberg H, Haefliger JA, Waeber G, Schuit F, Pipeleers D. Ling Z, et al. Among authors: heimberg h. Diabetes. 2003 Oct;52(10):2497-502. doi: 10.2337/diabetes.52.10.2497. Diabetes. 2003. PMID: 14514632

4

Prolonged culture in low glucose induces apoptosis of rat pancreatic beta-cells through induction of c-myc.

Van de Casteele M, Kefas BA, Cai Y, Heimberg H, Scott DK, Henquin JC, Pipeleers D, Jonas JC. Van de Casteele M, et al. Among authors: heimberg h. Biochem Biophys Res Commun. 2003 Dec 26;312(4):937-44. doi: 10.1016/j.bbrc.2003.11.013. Biochem Biophys Res Commun. 2003. PMID: 14651961

5

Adiponectin-mediated stimulation of AMP-activated protein kinase (AMPK) in pancreatic beta cells.

Huypens P, Moens K, Heimberg H, Ling Z, Pipeleers D, Van de Casteele M. Huypens P, et al. Among authors: heimberg h. Life Sci. 2005 Jul 29;77(11):1273-82. doi: 10.1016/j.lfs.2005.03.008. Life Sci. 2005. PMID: 15893773

6

Akt activation protects pancreatic beta cells from AMPK-mediated death through stimulation of mTOR.

Cai Y, Wang Q, Ling Z, Pipeleers D, McDermott P, Pende M, Heimberg H, Van de Casteele M. Cai Y, et al. Among authors: heimberg h. Biochem Pharmacol. 2008 May 15;75(10):1981-93. doi: 10.1016/j.bcp.2008.02.019. Epub 2008 Feb 26. Biochem Pharmacol. 2008. PMID: 18377870

7

AICA-riboside induces apoptosis of pancreatic beta cells through stimulation of AMP-activated protein kinase.

Kefas BA, Heimberg H, Vaulont S, Meisse D, Hue L, Pipeleers D, Van de Casteele M. Kefas BA, et al. Among authors: heimberg h. Diabetologia. 2003 Feb;46(2):250-4. doi: 10.1007/s00125-002-1030-3. Epub 2003 Feb 8. Diabetologia. 2003. PMID: 12627324

8

AMP-activated protein kinase can induce apoptosis of insulin-producing MIN6 cells through stimulation of c-Jun-N-terminal kinase.

Kefas BA, Cai Y, Ling Z, Heimberg H, Hue L, Pipeleers D, Van de Casteele M. Kefas BA, et al. Among authors: heimberg h. J Mol Endocrinol. 2003 Apr;30(2):151-61. doi: 10.1677/jme.0.0300151. J Mol Endocrinol. 2003. PMID: 12683939

9

Methyl succinate antagonises biguanide-induced AMPK-activation and death of pancreatic beta-cells through restoration of mitochondrial electron transfer.

Hinke SA, Martens GA, Cai Y, Finsi J, Heimberg H, Pipeleers D, Van de Casteele M. Hinke SA, et al. Among authors: heimberg h. Br J Pharmacol. 2007 Apr;150(8):1031-43. doi: 10.1038/sj.bjp.0707189. Epub 2007 Mar 5. Br J Pharmacol. 2007. PMID: 17339833 Free PMC article.

10

Glibenclamide activates translation in rat pancreatic beta cells through calcium-dependent mTOR, PKA and MEK signalling pathways.

Wang Q, Heimberg H, Pipeleers D, Ling Z. Wang Q, et al. Among authors: heimberg h. Diabetologia. 2008 Jul;51(7):1202-12. doi: 10.1007/s00125-008-1026-8. Epub 2008 May 21. Diabetologia. 2008. PMID: 18493739

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