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Human atherosclerotic intima and blood of patients with established coronary artery disease contain high density lipoprotein damaged by reactive nitrogen species.
Pennathur S, Bergt C, Shao B, Byun J, Kassim SY, Singh P, Green PS, McDonald TO, Brunzell J, Chait A, Oram JF, O'brien K, Geary RL, Heinecke JW. Pennathur S, et al. Among authors: heinecke jw. J Biol Chem. 2004 Oct 8;279(41):42977-83. doi: 10.1074/jbc.M406762200. Epub 2004 Aug 2. J Biol Chem. 2004. PMID: 15292228 Free article.
Hypochlorous acid generated by myeloperoxidase modifies adjacent tryptophan and glycine residues in the catalytic domain of matrix metalloproteinase-7 (matrilysin): an oxidative mechanism for restraining proteolytic activity during inflammation.
Fu X, Kassim SY, Parks WC, Heinecke JW. Fu X, et al. Among authors: heinecke jw. J Biol Chem. 2003 Aug 1;278(31):28403-9. doi: 10.1074/jbc.M304739200. Epub 2003 May 20. J Biol Chem. 2003. PMID: 12759346 Free article.
The myeloperoxidase product hypochlorous acid oxidizes HDL in the human artery wall and impairs ABCA1-dependent cholesterol transport.
Bergt C, Pennathur S, Fu X, Byun J, O'Brien K, McDonald TO, Singh P, Anantharamaiah GM, Chait A, Brunzell J, Geary RL, Oram JF, Heinecke JW. Bergt C, et al. Among authors: heinecke jw. Proc Natl Acad Sci U S A. 2004 Aug 31;101(35):13032-7. doi: 10.1073/pnas.0405292101. Epub 2004 Aug 23. Proc Natl Acad Sci U S A. 2004. PMID: 15326314 Free PMC article.
Acrolein modifies apolipoprotein A-I in the human artery wall.
Shao B, O'brien KD, McDonald TO, Fu X, Oram JF, Uchida K, Heinecke JW. Shao B, et al. Among authors: heinecke jw. Ann N Y Acad Sci. 2005 Jun;1043:396-403. doi: 10.1196/annals.1333.046. Ann N Y Acad Sci. 2005. PMID: 16037261
271 results