Settleman J - Search Results

1

The Drosophila ATM ortholog, dATM, mediates the response to ionizing radiation and to spontaneous DNA damage during development.

Song YH, Mirey G, Betson M, Haber DA, Settleman J. Song YH, et al. Among authors: settleman j. Curr Biol. 2004 Aug 10;14(15):1354-9. doi: 10.1016/j.cub.2004.06.064. Curr Biol. 2004. PMID: 15296752 Free article.

2

A rho-binding protein kinase C-like activity is required for the function of protein kinase N in Drosophila development.

Betson M, Settleman J. Betson M, et al. Among authors: settleman j. Genetics. 2007 Aug;176(4):2201-12. doi: 10.1534/genetics.107.072967. Epub 2007 May 16. Genetics. 2007. PMID: 17507675 Free PMC article.

3

Cell line-based platforms to evaluate the therapeutic efficacy of candidate anticancer agents.

Sharma SV, Haber DA, Settleman J. Sharma SV, et al. Among authors: settleman j. Nat Rev Cancer. 2010 Apr;10(4):241-53. doi: 10.1038/nrc2820. Epub 2010 Mar 19. Nat Rev Cancer. 2010. PMID: 20300105 Review.

4

Gefitinib-sensitizing EGFR mutations in lung cancer activate anti-apoptotic pathways.

Sordella R, Bell DW, Haber DA, Settleman J. Sordella R, et al. Among authors: settleman j. Science. 2004 Aug 20;305(5687):1163-7. doi: 10.1126/science.1101637. Epub 2004 Jul 29. Science. 2004. PMID: 15284455

5

Overcoming acquired resistance to Iressa/Tarceva with inhibitors of a different class.

Haber DA, Settleman J. Haber DA, et al. Among authors: settleman j. Cell Cycle. 2005 Aug;4(8):1057-9. Epub 2005 Aug 26. Cell Cycle. 2005. PMID: 15970680

6

Drosophila Rho-kinase (DRok) is required for tissue morphogenesis in diverse compartments of the egg chamber during oogenesis.

Verdier V, Johndrow JE, Betson M, Chen GC, Hughes DA, Parkhurst SM, Settleman J. Verdier V, et al. Among authors: settleman j. Dev Biol. 2006 Sep 15;297(2):417-32. doi: 10.1016/j.ydbio.2006.05.016. Epub 2006 May 19. Dev Biol. 2006. PMID: 16887114 Free PMC article.

7

Inherited susceptibility to lung cancer may be associated with the T790M drug resistance mutation in EGFR.

Bell DW, Gore I, Okimoto RA, Godin-Heymann N, Sordella R, Mulloy R, Sharma SV, Brannigan BW, Mohapatra G, Settleman J, Haber DA. Bell DW, et al. Among authors: settleman j. Nat Genet. 2005 Dec;37(12):1315-6. doi: 10.1038/ng1671. Epub 2005 Oct 30. Nat Genet. 2005. PMID: 16258541

8

"Oncogenic shock": explaining oncogene addiction through differential signal attenuation.

Sharma SV, Fischbach MA, Haber DA, Settleman J. Sharma SV, et al. Among authors: settleman j. Clin Cancer Res. 2006 Jul 15;12(14 Pt 2):4392s-4395s. doi: 10.1158/1078-0432.CCR-06-0096. Clin Cancer Res. 2006. PMID: 16857816 Review.

9

A common signaling cascade may underlie "addiction" to the Src, BCR-ABL, and EGF receptor oncogenes.

Sharma SV, Gajowniczek P, Way IP, Lee DY, Jiang J, Yuza Y, Classon M, Haber DA, Settleman J. Sharma SV, et al. Among authors: settleman j. Cancer Cell. 2006 Nov;10(5):425-35. doi: 10.1016/j.ccr.2006.09.014. Cancer Cell. 2006. PMID: 17097564 Free PMC article.

10

Epidermal growth factor receptor mutations in lung cancer.

Sharma SV, Bell DW, Settleman J, Haber DA. Sharma SV, et al. Among authors: settleman j. Nat Rev Cancer. 2007 Mar;7(3):169-81. doi: 10.1038/nrc2088. Nat Rev Cancer. 2007. PMID: 17318210 Review.

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