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Structural relationship of lithocholic acid derivatives binding to the N-terminal 8-kDa domain of DNA polymerase beta.
Mizushina Y, Kasai N, Miura K, Hanashima S, Takemura M, Yoshida H, Sugawara F, Sakaguchi K. Mizushina Y, et al. Among authors: sakaguchi k. Biochemistry. 2004 Aug 24;43(33):10669-77. doi: 10.1021/bi049307r. Biochemistry. 2004. PMID: 15311928
We reported previously that lithocholic acid (LCA, 3-alpha-hydroxy-5-beta-cholan-24-oic acid), one of the major compounds in the secondary bile acids, selectively inhibited the activity of mammalian DNA polymerase beta (pol beta) [Mizushina, Y., Ohkubo, T., Sugawara, F., and S …
We reported previously that lithocholic acid (LCA, 3-alpha-hydroxy-5-beta-cholan-24-oic acid), one of the major compounds in the secondary b …
A plant phytotoxin, solanapyrone A, is an inhibitor of DNA polymerase beta and lambda.
Mizushina Y, Kamisuki S, Kasai N, Shimazaki N, Takemura M, Asahara H, Linn S, Yoshida S, Matsukage A, Koiwai O, Sugawara F, Yoshida H, Sakaguchi K. Mizushina Y, et al. Among authors: sakaguchi k. J Biol Chem. 2002 Jan 4;277(1):630-8. doi: 10.1074/jbc.M105144200. Epub 2001 Oct 24. J Biol Chem. 2002. PMID: 11677229 Free article.
Anti-tumor effect of chemically synthesized sulfolipids based on sea urchin's natural sulfonoquinovosylmonoacylglycerols.
Sahara H, Hanashima S, Yamazaki T, Takahashi S, Sugawara F, Ohtani S, Ishikawa M, Mizushina Y, Ohta K, Shimozawa K, Gasa S, Jimbow K, Sakaguchi K, Sato N, Takahashi N. Sahara H, et al. Among authors: sakaguchi k. Jpn J Cancer Res. 2002 Jan;93(1):85-92. doi: 10.1111/j.1349-7006.2002.tb01204.x. Jpn J Cancer Res. 2002. PMID: 11802812 Free PMC article.
Vitamin A-related compounds, all-trans retinal and retinoic acids, selectively inhibit activities of mammalian replicative DNA polymerases.
Murakami C, Takemura M, Sugiyama Y, Kamisuki S, Asahara H, Kawasaki M, Ishidoh T, Linn S, Yoshida S, Sugawara F, Yoshida H, Sakaguchi K, Mizushina Y. Murakami C, et al. Among authors: sakaguchi k. Biochim Biophys Acta. 2002 Feb 20;1574(1):85-92. doi: 10.1016/s0167-4781(01)00348-7. Biochim Biophys Acta. 2002. PMID: 11955616
[Inhibitors of eukaryotic DNA polymerases].
Sakaguchi K, Sugawara F, Mizushina Y. Sakaguchi K, et al. Seikagaku. 2002 Mar;74(3):244-51. Seikagaku. 2002. PMID: 11974919 Japanese. No abstract available.
1,559 results