Kowalski TJ - Search Results

1

Melanin-concentrating hormone-1 receptor antagonism decreases feeding by reducing meal size.

Kowalski TJ, Farley C, Cohen-Williams ME, Varty G, Spar BD. Kowalski TJ, et al. Eur J Pharmacol. 2004 Aug 16;497(1):41-7. doi: 10.1016/j.ejphar.2004.06.027. Eur J Pharmacol. 2004. PMID: 15321733

2

Meal pattern analysis of diet-induced obesity in susceptible and resistant rats.

Farley C, Cook JA, Spar BD, Austin TM, Kowalski TJ. Farley C, et al. Among authors: kowalski tj. Obes Res. 2003 Jul;11(7):845-51. doi: 10.1038/oby.2003.116. Obes Res. 2003. PMID: 12855753 Free article.

3

Discovery of bicycloalkyl urea melanin concentrating hormone receptor antagonists: orally efficacious antiobesity therapeutics.

McBriar MD, Guzik H, Xu R, Paruchova J, Li S, Palani A, Clader JW, Greenlee WJ, Hawes BE, Kowalski TJ, O'Neill K, Spar B, Weig B. McBriar MD, et al. Among authors: kowalski tj. J Med Chem. 2005 Apr 7;48(7):2274-7. doi: 10.1021/jm049035q. J Med Chem. 2005. PMID: 15801820

4

Biaryl ureas as potent and orally efficacious melanin concentrating hormone receptor 1 antagonists for the treatment of obesity.

Palani A, Shapiro S, McBriar MD, Clader JW, Greenlee WJ, Spar B, Kowalski TJ, Farley C, Cook J, van Heek M, Weig B, O'neill K, Graziano M, Hawes B. Palani A, et al. Among authors: kowalski tj. J Med Chem. 2005 Jul 28;48(15):4746-9. doi: 10.1021/jm0503852. J Med Chem. 2005. PMID: 16033253

5

Bicyclic[4.1.0]heptanes as phenyl replacements for melanin concentrating hormone receptor antagonists.

Xu R, Li S, Paruchova J, McBriar MD, Guzik H, Palani A, Clader JW, Cox K, Greenlee WJ, Hawes BE, Kowalski TJ, O'Neill K, Spar BD, Weig B, Weston DJ. Xu R, et al. Among authors: kowalski tj. Bioorg Med Chem. 2006 May 15;14(10):3285-99. doi: 10.1016/j.bmc.2005.12.046. Epub 2006 Jan 26. Bioorg Med Chem. 2006. PMID: 16442800

6

Effects of a selective melanin-concentrating hormone 1 receptor antagonist on food intake and energy homeostasis in diet-induced obese mice.

Kowalski TJ, Spar BD, Weig B, Farley C, Cook J, Ghibaudi L, Fried S, O'Neill K, Del Vecchio RA, McBriar M, Guzik H, Clader J, Hawes BE, Hwa J. Kowalski TJ, et al. Eur J Pharmacol. 2006 Mar 27;535(1-3):182-91. doi: 10.1016/j.ejphar.2006.01.062. Epub 2006 Mar 13. Eur J Pharmacol. 2006. PMID: 16540104

7

Discovery of orally efficacious melanin-concentrating hormone receptor-1 antagonists as antiobesity agents. Synthesis, SAR, and biological evaluation of bicyclo[3.1.0]hexyl ureas.

McBriar MD, Guzik H, Shapiro S, Paruchova J, Xu R, Palani A, Clader JW, Cox K, Greenlee WJ, Hawes BE, Kowalski TJ, O'neill K, Spar BD, Weig B, Weston DJ, Farley C, Cook J. McBriar MD, et al. Among authors: kowalski tj. J Med Chem. 2006 Apr 6;49(7):2294-310. doi: 10.1021/jm050886n. J Med Chem. 2006. PMID: 16570926

8

Transgenic overexpression of neuromedin U promotes leanness and hypophagia in mice.

Kowalski TJ, Spar BD, Markowitz L, Maguire M, Golovko A, Yang S, Farley C, Cook JA, Tetzloff G, Hoos L, Del Vecchio RA, Kazdoba TM, McCool MF, Hwa JJ, Hyde LA, Davis H, Vassileva G, Hedrick JA, Gustafson EL. Kowalski TJ, et al. J Endocrinol. 2005 Apr;185(1):151-64. doi: 10.1677/joe.1.05948. J Endocrinol. 2005. PMID: 15817836

9

Design and synthesis of orally efficacious benzimidazoles as melanin-concentrating hormone receptor 1 antagonists.

Wu WL, Burnett DA, Caplen MA, Domalski MS, Bennett C, Greenlee WJ, Hawes BE, O'Neill K, Weig B, Weston D, Spar B, Kowalski T. Wu WL, et al. Bioorg Med Chem Lett. 2006 Jul 15;16(14):3674-8. doi: 10.1016/j.bmcl.2006.04.062. Epub 2006 May 11. Bioorg Med Chem Lett. 2006. PMID: 16690315

10

SAR study of bicyclo[4.1.0]heptanes as melanin-concentrating hormone receptor R1 antagonists: taming hERG.

Su J, McKittrick BA, Tang H, Burnett DA, Clader JW, Greenlee WJ, Hawes BE, O'Neill K, Spar B, Weig B, Kowalski T, Sorota S, Li C, Liu T. Su J, et al. Bioorg Med Chem. 2007 Aug 15;15(16):5369-85. doi: 10.1016/j.bmc.2007.05.068. Epub 2007 Jun 2. Bioorg Med Chem. 2007. PMID: 17572094

Save citations to file

Email citations

Send citations to clipboard

Add to Collections

Add to My Bibliography

Create a file for external citation management software

Your saved search

Your RSS Feed

My Custom Filters

Publication date

Text availability

Article attribute

Article type

Article Language

Species

Sex

Age

Other

111 results

Search Page

Filters