Koren AO - Search Results

1

Pharmacological and toxicological evaluation of 2-fluoro-3-(2(S)-azetidinylmethoxy)pyridine (2-F-A-85380), a ligand for imaging cerebral nicotinic acetylcholine receptors with positron emission tomography.

Vaupel DB, Tella SR, Huso DL, Wagner VO 3rd, Mukhin AG, Chefer SI, Horti AG, London ED, Koren AO, Kimes AS. Vaupel DB, et al. Among authors: koren ao. J Pharmacol Exp Ther. 2005 Jan;312(1):355-65. doi: 10.1124/jpet.104.073999. Epub 2004 Aug 26. J Pharmacol Exp Ther. 2005. PMID: 15331657

2

Synthesis and evaluation of a novel series of 2-chloro-5-((1-methyl-2-(S)-pyrrolidinyl)methoxy)-3-(2-(4-pyridinyl)vinyl)pyridine analogues as potential positron emission tomography imaging agents for nicotinic acetylcholine receptors.

Brown LL, Kulkarni S, Pavlova OA, Koren AO, Mukhin AG, Newman AH, Horti AG. Brown LL, et al. Among authors: koren ao. J Med Chem. 2002 Jun 20;45(13):2841-9. doi: 10.1021/jm010550n. J Med Chem. 2002. PMID: 12061886

3

Graphical analysis of 2-[18F]FA binding to nicotinic acetylcholine receptors in rhesus monkey brain.

Chefer SI, London ED, Koren AO, Pavlova OA, Kurian V, Kimes AS, Horti AG, Mukhin AG. Chefer SI, et al. Among authors: koren ao. Synapse. 2003 Apr;48(1):25-34. doi: 10.1002/syn.10180. Synapse. 2003. PMID: 12557269

4

2-[18F]F-A-85380: PET imaging of brain nicotinic acetylcholine receptors and whole body distribution in humans.

Kimes AS, Horti AG, London ED, Chefer SI, Contoreggi C, Ernst M, Friello P, Koren AO, Kurian V, Matochik JA, Pavlova O, Vaupel DB, Mukhin AG. Kimes AS, et al. Among authors: koren ao. FASEB J. 2003 Jul;17(10):1331-3. doi: 10.1096/fj.02-0492fje. Epub 2003 May 20. FASEB J. 2003. PMID: 12759330

5

Evaluation of 5-(2-(4-pyridinyl)vinyl)-6-chloro-3-(1-methyl-2-(S)-pyrrolidinylmethoxy)pyridine and its analogues as PET radioligands for imaging nicotinic acetylcholine receptors.

Brown L, Chefer S, Pavlova O, Vaupel DB, Koren AO, Kimes AS, Horti AG, Mukhin AG. Brown L, et al. Among authors: koren ao. J Neurochem. 2004 Nov;91(3):600-12. doi: 10.1111/j.1471-4159.2004.02762.x. J Neurochem. 2004. PMID: 15485491 Free article.

6

In vitro characterization of 6-[18F]fluoro-A-85380, a high-affinity ligand for alpha4beta2* nicotinic acetylcholine receptors.

Gündisch D, Koren AO, Horti AG, Pavlova OA, Kimes AS, Mukhin AG, London ED. Gündisch D, et al. Among authors: koren ao. Synapse. 2005 Feb;55(2):89-97. doi: 10.1002/syn.20096. Synapse. 2005. PMID: 15529332

7

2-, 5-, and 6-Halo-3-(2(S)-azetidinylmethoxy)pyridines: synthesis, affinity for nicotinic acetylcholine receptors, and molecular modeling.

Koren AO, Horti AG, Mukhin AG, Gündisch D, Kimes AS, Dannals RF, London ED. Koren AO, et al. J Med Chem. 1998 Sep 10;41(19):3690-8. doi: 10.1021/jm980170a. J Med Chem. 1998. PMID: 9733494

8

2-[18F]Fluoro-A-85380, an in vivo tracer for the nicotinic acetylcholine receptors.

Horti AG, Scheffel U, Koren AO, Ravert HT, Mathews WB, Musachio JL, Finley PA, London ED, Dannals RF. Horti AG, et al. Among authors: koren ao. Nucl Med Biol. 1998 Oct;25(7):599-603. doi: 10.1016/s0969-8051(98)00031-6. Nucl Med Biol. 1998. PMID: 9804040 Free article.

9

5-Iodo-A-85380, an alpha4beta2 subtype-selective ligand for nicotinic acetylcholine receptors.

Mukhin AG, Gündisch D, Horti AG, Koren AO, Tamagnan G, Kimes AS, Chambers J, Vaupel DB, King SL, Picciotto MR, Innis RB, London ED. Mukhin AG, et al. Among authors: koren ao. Mol Pharmacol. 2000 Mar;57(3):642-9. doi: 10.1124/mol.57.3.642. Mol Pharmacol. 2000. PMID: 10692507

10

6-[18F]fluoro-A-85380, a novel radioligand for in vivo imaging of central nicotinic acetylcholine receptors.

Horti AG, Chefer SI, Mukhin AG, Koren AO, Gündisch D, Links JM, Kurian V, Dannals RF, London ED. Horti AG, et al. Among authors: koren ao. Life Sci. 2000 Jun 16;67(4):463-9. doi: 10.1016/s0024-3205(00)00635-4. Life Sci. 2000. PMID: 11003056

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