Gobbi M - Search Results

1

Structure-affinity studies for a novel series of homochiral naphtho and tetrahydronaphtho analogues of alpha 1 antagonist WB-4101.

Bolchi C, Catalano P, Fumagalli L, Gobbi M, Pallavicini M, Pedretti A, Villa L, Vistoli G, Valoti E. Bolchi C, et al. Among authors: gobbi m. Bioorg Med Chem. 2004 Sep 15;12(18):4937-51. doi: 10.1016/j.bmc.2004.06.040. Bioorg Med Chem. 2004. PMID: 15336273

2

QSAR study for a novel series of ortho monosubstituted phenoxy analogues of alpha1-adrenoceptor antagonist WB4101.

Fumagalli L, Bolchi C, Colleoni S, Gobbi M, Moroni B, Pallavicini M, Pedretti A, Villa L, Vistoli G, Valoti E. Fumagalli L, et al. Among authors: gobbi m. Bioorg Med Chem. 2005 Apr 1;13(7):2547-59. doi: 10.1016/j.bmc.2005.01.034. Bioorg Med Chem. 2005. PMID: 15755656

3

QSAR study for a novel series of ortho disubstituted phenoxy analogues of alpha1-adrenoceptor antagonist WB4101.

Pallavicini M, Fumagalli L, Gobbi M, Bolchi C, Colleoni S, Moroni B, Pedretti A, Rusconi C, Vistoli G, Valoti E. Pallavicini M, et al. Among authors: gobbi m. Eur J Med Chem. 2006 Sep;41(9):1025-40. doi: 10.1016/j.ejmech.2006.04.004. Epub 2006 Jun 5. Eur J Med Chem. 2006. PMID: 16737760

4

WB4101-related compounds: new, subtype-selective alpha1-adrenoreceptor antagonists (or inverse agonists?).

Pallavicini M, Budriesi R, Fumagalli L, Ioan P, Chiarini A, Bolchi C, Ugenti MP, Colleoni S, Gobbi M, Valoti E. Pallavicini M, et al. Among authors: gobbi m. J Med Chem. 2006 Nov 30;49(24):7140-9. doi: 10.1021/jm060358r. J Med Chem. 2006. PMID: 17125266

5

A novel spirocyclic tropanyl-Δ²-isoxazoline derivative enhances citalopram and paroxetine binding to serotonin transporters as well as serotonin uptake.

Dallanoce C, Canovi M, Matera C, Mennini T, De Amici M, Gobbi M, De Micheli C. Dallanoce C, et al. Among authors: gobbi m. Bioorg Med Chem. 2012 Nov 1;20(21):6344-55. doi: 10.1016/j.bmc.2012.09.004. Epub 2012 Sep 10. Bioorg Med Chem. 2012. PMID: 23022052

6

Affinity and activity profiling of unichiral 8-substituted 1,4-benzodioxane analogues of WB4101 reveals a potent and selective α1B-adrenoceptor antagonist.

Fumagalli L, Pallavicini M, Budriesi R, Gobbi M, Straniero V, Zagami M, Chiodini G, Bolchi C, Chiarini A, Micucci M, Valoti E. Fumagalli L, et al. Among authors: gobbi m. Eur J Med Chem. 2012 Dec;58:184-91. doi: 10.1016/j.ejmech.2012.09.049. Epub 2012 Oct 16. Eur J Med Chem. 2012. PMID: 23124215

7

6-methoxy-7-benzofuranoxy and 6-methoxy-7-indolyloxy analogues of 2-[2-(2,6-Dimethoxyphenoxy)ethyl]aminomethyl-1,4-benzodioxane (WB4101):1 discovery of a potent and selective α1D-adrenoceptor antagonist.

Fumagalli L, Pallavicini M, Budriesi R, Bolchi C, Canovi M, Chiarini A, Chiodini G, Gobbi M, Laurino P, Micucci M, Straniero V, Valoti E. Fumagalli L, et al. Among authors: gobbi m. J Med Chem. 2013 Aug 22;56(16):6402-12. doi: 10.1021/jm400867d. Epub 2013 Jul 31. J Med Chem. 2013. PMID: 23902232

8

Antagonist properties of 1-(2-pyrimidinyl)piperazine at presynaptic alpha 2-adrenoceptors in the rat brain.

Gobbi M, Frittoli E, Mennini T. Gobbi M, et al. Eur J Pharmacol. 1990 May 3;180(1):183-6. doi: 10.1016/0014-2999(90)90608-9. Eur J Pharmacol. 1990. PMID: 1973112

9

The modulation of [3H]noradrenaline and [3H]serotonin release from rat brain synaptosomes is not mediated by the alpha 2B-adrenoceptor subtype.

Gobbi M, Frittoli E, Mennini T. Gobbi M, et al. Naunyn Schmiedebergs Arch Pharmacol. 1990 Oct;342(4):382-6. doi: 10.1007/BF00169453. Naunyn Schmiedebergs Arch Pharmacol. 1990. PMID: 1979424

10

Biochemical characterization of a new highly cardioselective beta-adrenoceptor antagonist.

Gobbi M, Mennini T, Ratti E. Gobbi M, et al. J Pharm Pharmacol. 1988 Apr;40(4):243-6. doi: 10.1111/j.2042-7158.1988.tb05236.x. J Pharm Pharmacol. 1988. PMID: 2900302

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