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The G/G genotype of a resistin single-nucleotide polymorphism at -420 increases type 2 diabetes mellitus susceptibility by inducing promoter activity through specific binding of Sp1/3.
Osawa H, Yamada K, Onuma H, Murakami A, Ochi M, Kawata H, Nishimiya T, Niiya T, Shimizu I, Nishida W, Hashiramoto M, Kanatsuka A, Fujii Y, Ohashi J, Makino H. Osawa H, et al. Among authors: hashiramoto m. Am J Hum Genet. 2004 Oct;75(4):678-86. doi: 10.1086/424761. Epub 2004 Aug 26. Am J Hum Genet. 2004. PMID: 15338456 Free PMC article.
A pilot study suggests that the G/G genotype of resistin single nucleotide polymorphism at -420 may be an independent predictor of a reduction in fasting plasma glucose and insulin resistance by pioglitazone in type 2 diabetes.
Makino H, Shimizu I, Murao S, Kondo S, Tabara Y, Fujiyama M, Fujii Y, Takada Y, Nakai K, Izumi K, Ohashi J, Kawamura R, Yamauchi J, Takata Y, Nishida W, Hashiramoto M, Onuma H, Osawa H. Makino H, et al. Among authors: hashiramoto m. Endocr J. 2009;56(9):1049-58. doi: 10.1507/endocrj.k08e-320. Epub 2009 Sep 9. Endocr J. 2009. PMID: 19738363 Free article.
Long-term safety and efficacy of alogliptin, a DPP-4 inhibitor, in patients with type 2 diabetes: a 3-year prospective, controlled, observational study (J-BRAND Registry).
Ueki K, Tanizawa Y, Nakamura J, Yamada Y, Inagaki N, Watada H, Shimomura I, Nishimura R, Miyoshi H, Abiko A, Katagiri H, Hayashi M, Shimada A, Naruse K, Fujimoto S, Fujiwara M, Shikata K, Okada Y, Araki E, Yamazaki T, Kadowaki T; J-BRAND Registry Group. Ueki K, et al. BMJ Open Diabetes Res Care. 2021 Jan;9(1):e001787. doi: 10.1136/bmjdrc-2020-001787. BMJ Open Diabetes Res Care. 2021. PMID: 33441417 Free PMC article.
Molecular analysis of db gene-related pancreatic beta cell dysfunction; evidence for a compensatory mechanism inhibiting development of diabetes in the db gene heterozygote.
Kanda Y, Shimoda M, Tawaramoto K, Hamamoto S, Tatsumi F, Kawasaki F, Hashiramoto M, Nakashima K, Matsuki M, Kaku K. Kanda Y, et al. Among authors: hashiramoto m. Endocr J. 2009;56(8):997-1008. doi: 10.1507/endocrj.k09e-028. Epub 2009 Aug 25. Endocr J. 2009. PMID: 19706988 Free article.
56 results