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The G/G genotype of a resistin single-nucleotide polymorphism at -420 increases type 2 diabetes mellitus susceptibility by inducing promoter activity through specific binding of Sp1/3.
Osawa H, Yamada K, Onuma H, Murakami A, Ochi M, Kawata H, Nishimiya T, Niiya T, Shimizu I, Nishida W, Hashiramoto M, Kanatsuka A, Fujii Y, Ohashi J, Makino H. Osawa H, et al. Among authors: murakami a. Am J Hum Genet. 2004 Oct;75(4):678-86. doi: 10.1086/424761. Epub 2004 Aug 26. Am J Hum Genet. 2004. PMID: 15338456 Free PMC article.
A systematic search for single nucleotide polymorphisms (SNPs) in the insulin receptor gene: association of an SNP with hyperlipidemia in Japanese type 2 diabetic subjects.
Osawa H, Ochi M, Nishimiya T, Onuma H, Nakamaru K, Murakami A, Kato K, Shimizu I, Fujii Y, Ohashi J, Makino H. Osawa H, et al. Among authors: murakami a. Clin Genet. 2001 Dec;60(6):479-81. doi: 10.1034/j.1399-0004.2001.600615.x. Clin Genet. 2001. PMID: 11846745 No abstract available.
Systematic search for single nucleotide polymorphisms in the FOXC2 gene: the absence of evidence for the association of three frequent single nucleotide polymorphisms and four common haplotypes with Japanese type 2 diabetes.
Osawa H, Onuma H, Murakami A, Ochi M, Nishimiya T, Kato K, Shimizu I, Fujii Y, Ohashi J, Makino H. Osawa H, et al. Among authors: murakami a. Diabetes. 2003 Feb;52(2):562-7. doi: 10.2337/diabetes.52.2.562. Diabetes. 2003. PMID: 12540636
Systematic search for single nucleotide polymorphisms in the 5' flanking region of the human phosphodiesterase 3B gene: absence of evidence for major effects of identified polymorphisms on susceptibility to Japanese type 2 diabetes.
Osawa H, Niiya T, Onuma H, Murakami A, Ochi M, Nishimiya T, Ogura T, Kato K, Shimizu I, Fujii Y, Ohashi J, Yamada K, Liang SJ, Manganiello VC, Fujita-Yamaguchi Y, Makino H. Osawa H, et al. Among authors: murakami a. Mol Genet Metab. 2003 May;79(1):43-51. doi: 10.1016/s1096-7192(03)00035-0. Mol Genet Metab. 2003. PMID: 12765845
The absence of evidence for major effects of the frequent SNP +299G>A in the resistin gene on susceptibility to insulin resistance syndrome associated with Japanese type 2 diabetes.
Ochi M, Osawa H, Onuma H, Murakami A, Nishimiya T, Shimada F, Kato K, Shimizu I, Shishino K, Murase M, Fujii Y, Ohashi J, Makino H. Ochi M, et al. Among authors: murakami a. Diabetes Res Clin Pract. 2003 Sep;61(3):191-8. doi: 10.1016/s0168-8227(03)00119-0. Diabetes Res Clin Pract. 2003. PMID: 12965109
Resistin SNP-420 determines its monocyte mRNA and serum levels inducing type 2 diabetes.
Osawa H, Onuma H, Ochi M, Murakami A, Yamauchi J, Takasuka T, Tanabe F, Shimizu I, Kato K, Nishida W, Yamada K, Tabara Y, Yasukawa M, Fujii Y, Ohashi J, Miki T, Makino H. Osawa H, et al. Among authors: murakami a. Biochem Biophys Res Commun. 2005 Sep 23;335(2):596-602. doi: 10.1016/j.bbrc.2005.07.122. Biochem Biophys Res Commun. 2005. PMID: 16087164
1,699 results