Frame MC - Search Results

1

SRC-mediated phosphorylation of focal adhesion kinase couples actin and adhesion dynamics to survival signaling.

Westhoff MA, Serrels B, Fincham VJ, Frame MC, Carragher NO. Westhoff MA, et al. Among authors: frame mc. Mol Cell Biol. 2004 Sep;24(18):8113-33. doi: 10.1128/MCB.24.18.8113-8133.2004. Mol Cell Biol. 2004. PMID: 15340073 Free PMC article.

2

Separation of v-Src-induced mitogenesis and morphological transformation by inhibition of AP-1.

Frame MC, Simpson K, Fincham VJ, Crouch DH. Frame MC, et al. Mol Biol Cell. 1994 Nov;5(11):1177-84. doi: 10.1091/mbc.5.11.1177. Mol Biol Cell. 1994. PMID: 7865883 Free PMC article.

3

Targeted proteolysis of the focal adhesion kinase pp125 FAK during c-MYC-induced apoptosis is suppressed by integrin signalling.

Crouch DH, Fincham VJ, Frame MC. Crouch DH, et al. Among authors: frame mc. Oncogene. 1996 Jun 20;12(12):2689-96. Oncogene. 1996. PMID: 8700528

4

Translocation of Src kinase to the cell periphery is mediated by the actin cytoskeleton under the control of the Rho family of small G proteins.

Fincham VJ, Unlu M, Brunton VG, Pitts JD, Wyke JA, Frame MC. Fincham VJ, et al. Among authors: frame mc. J Cell Biol. 1996 Dec;135(6 Pt 1):1551-64. doi: 10.1083/jcb.135.6.1551. J Cell Biol. 1996. PMID: 8978822 Free PMC article.

5

The catalytic activity of Src is dispensable for translocation to focal adhesions but controls the turnover of these structures during cell motility.

Fincham VJ, Frame MC. Fincham VJ, et al. Among authors: frame mc. EMBO J. 1998 Jan 2;17(1):81-92. doi: 10.1093/emboj/17.1.81. EMBO J. 1998. PMID: 9427743 Free PMC article.

6

Regulation of p190 Rho-GAP by v-Src is linked to cytoskeletal disruption during transformation.

Fincham VJ, Chudleigh A, Frame MC. Fincham VJ, et al. Among authors: frame mc. J Cell Sci. 1999 Mar;112 ( Pt 6):947-56. doi: 10.1242/jcs.112.6.947. J Cell Sci. 1999. PMID: 10036244

7

v-Src induces tyrosine phosphorylation of focal adhesion kinase independently of tyrosine 397 and formation of a complex with Src.

McLean GW, Fincham VJ, Frame MC. McLean GW, et al. Among authors: frame mc. J Biol Chem. 2000 Jul 28;275(30):23333-9. doi: 10.1074/jbc.M909322199. J Biol Chem. 2000. PMID: 10816598 Free article.

8

Active ERK/MAP kinase is targeted to newly forming cell-matrix adhesions by integrin engagement and v-Src.

Fincham VJ, James M, Frame MC, Winder SJ. Fincham VJ, et al. Among authors: frame mc. EMBO J. 2000 Jun 15;19(12):2911-23. doi: 10.1093/emboj/19.12.2911. EMBO J. 2000. PMID: 10856236 Free PMC article.

9

The SH3 domain directs acto-myosin-dependent targeting of v-Src to focal adhesions via phosphatidylinositol 3-kinase.

Fincham VJ, Brunton VG, Frame MC. Fincham VJ, et al. Among authors: frame mc. Mol Cell Biol. 2000 Sep;20(17):6518-36. doi: 10.1128/MCB.20.17.6518-6536.2000. Mol Cell Biol. 2000. PMID: 10938128 Free PMC article.

10

Cleavage of focal adhesion kinase by different proteases during SRC-regulated transformation and apoptosis. Distinct roles for calpain and caspases.

Carragher NO, Fincham VJ, Riley D, Frame MC. Carragher NO, et al. Among authors: frame mc. J Biol Chem. 2001 Feb 9;276(6):4270-5. doi: 10.1074/jbc.M008972200. Epub 2000 Nov 7. J Biol Chem. 2001. PMID: 11069922 Free article.

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