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Estrogen enhances depolarization-induced glutamate release through activation of phosphatidylinositol 3-kinase and mitogen-activated protein kinase in cultured hippocampal neurons.
Yokomaku D, Numakawa T, Numakawa Y, Suzuki S, Matsumoto T, Adachi N, Nishio C, Taguchi T, Hatanaka H. Yokomaku D, et al. Among authors: numakawa y, numakawa t. Mol Endocrinol. 2003 May;17(5):831-44. doi: 10.1210/me.2002-0314. Epub 2003 Jan 23. Mol Endocrinol. 2003. PMID: 12554763
Chronic antidepressants potentiate via sigma-1 receptors the brain-derived neurotrophic factor-induced signaling for glutamate release.
Yagasaki Y, Numakawa T, Kumamaru E, Hayashi T, Su TP, Kunugi H. Yagasaki Y, et al. Among authors: numakawa t. J Biol Chem. 2006 May 5;281(18):12941-9. doi: 10.1074/jbc.M508157200. Epub 2006 Mar 6. J Biol Chem. 2006. PMID: 16522641 Free article.
Because BDNF has been shown by us to reinforce excitatory glutamatergic transmission in cultured cortical neurons via the phospholipase-gamma (PLC-gamma)/inositol 1,4,5-trisphosphate (IP3)/Ca2+ pathway (Numakawa, T., Yamagishi, S., Adachi, N., Matsumoto, T., …
Because BDNF has been shown by us to reinforce excitatory glutamatergic transmission in cultured cortical neurons via the phospholipase-gamm …
Impact of the DISC1 Ser704Cys polymorphism on risk for major depression, brain morphology and ERK signaling.
Hashimoto R, Numakawa T, Ohnishi T, Kumamaru E, Yagasaki Y, Ishimoto T, Mori T, Nemoto K, Adachi N, Izumi A, Chiba S, Noguchi H, Suzuki T, Iwata N, Ozaki N, Taguchi T, Kamiya A, Kosuga A, Tatsumi M, Kamijima K, Weinberger DR, Sawa A, Kunugi H. Hashimoto R, et al. Among authors: numakawa t. Hum Mol Genet. 2006 Oct 15;15(20):3024-33. doi: 10.1093/hmg/ddl244. Epub 2006 Sep 7. Hum Mol Genet. 2006. PMID: 16959794
88 results