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Preclinical development of a bispecific TNFα/IL-23 neutralising domain antibody as a novel oral treatment for inflammatory bowel disease.
Roberts KJ, Cubitt MF, Carlton TM, Rodrigues-Duarte L, Maggiore L, Chai R, Clare S, Harcourt K, MacDonald TT, Ray KP, Vossenkämper A, West MR, Crowe JS. Roberts KJ, et al. Among authors: vossenkamper a. Sci Rep. 2021 Sep 30;11(1):19422. doi: 10.1038/s41598-021-97236-0. Sci Rep. 2021. PMID: 34593832 Free PMC article.
Oral Anti-Tumour Necrosis Factor Domain Antibody V565 Provides High Intestinal Concentrations, and Reduces Markers of Inflammation in Ulcerative Colitis Patients.
Nurbhai S, Roberts KJ, Carlton TM, Maggiore L, Cubitt MF, Ray KP, Reckless J, Mohammed H, Irving P, MacDonald TT, Vossenkämper A, West MR, Parkes GC, Crowe JS. Nurbhai S, et al. Among authors: vossenkamper a. Sci Rep. 2019 Oct 1;9(1):14042. doi: 10.1038/s41598-019-50545-x. Sci Rep. 2019. PMID: 31575982 Free PMC article.
Preclinical evaluation of EPHX2 inhibition as a novel treatment for inflammatory bowel disease.
Reisdorf WC, Xie Q, Zeng X, Xie W, Rajpal N, Hoang B, Burgert ME, Kumar V, Hurle MR, Rajpal DK, O'Donnell S, MacDonald TT, Vossenkämper A, Wang L, Reilly M, Votta BJ, Sanchez Y, Agarwal P. Reisdorf WC, et al. Among authors: vossenkamper a. PLoS One. 2019 Apr 19;14(4):e0215033. doi: 10.1371/journal.pone.0215033. eCollection 2019. PLoS One. 2019. PMID: 31002701 Free PMC article.
Proteolytic cleavage and loss of function of biologic agents that neutralize tumor necrosis factor in the mucosa of patients with inflammatory bowel disease.
Biancheri P, Brezski RJ, Di Sabatino A, Greenplate AR, Soring KL, Corazza GR, Kok KB, Rovedatti L, Vossenkämper A, Ahmad N, Snoek SA, Vermeire S, Rutgeerts P, Jordan RE, MacDonald TT. Biancheri P, et al. Among authors: vossenkamper a. Gastroenterology. 2015 Nov;149(6):1564-1574.e3. doi: 10.1053/j.gastro.2015.07.002. Epub 2015 Jul 11. Gastroenterology. 2015. PMID: 26170138 Free article.
A functional IL1RL1 variant regulates corticosteroid-induced sST2 expression in ulcerative colitis.
Díaz-Jiménez D, Núñez L, De la Fuente M, Dubois-Camacho K, Sepúlveda H, Montecino M, Torres-Riquelme A, García-González P, Chnaiderman J, Vossenkamper A, MacDonald TT, Simian D, González MJ, Cidlowski JA, Quera R, Hermoso MA. Díaz-Jiménez D, et al. Among authors: vossenkamper a. Sci Rep. 2017 Aug 31;7(1):10180. doi: 10.1038/s41598-017-10465-0. Sci Rep. 2017. PMID: 28860510 Free PMC article.
33 results