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Quinazolinone fungal efflux pump inhibitors. Part 2: In vitro structure-activity relationships of (N-methyl-piperazinyl)-containing derivatives.
Watkins WJ, Lemoine RC, Chong L, Cho A, Renau TE, Kuo B, Wong V, Ludwikow M, Garizi N, Iqbal N, Barnard J, Jankowska R, Singh R, Madsen D, Lolans K, Lomovskaya O, Oza U, Dudley MN. Watkins WJ, et al. Among authors: lolans k. Bioorg Med Chem Lett. 2004 Oct 18;14(20):5133-7. doi: 10.1016/j.bmcl.2004.07.071. Bioorg Med Chem Lett. 2004. PMID: 15380214
Quinazolinone-based fungal efflux pump inhibitors. Part 1: Discovery of an (N-methylpiperazine)-containing derivative with activity in clinically relevant Candida spp.
Lemoine RC, Glinka TW, Watkins WJ, Cho A, Yang J, Iqbal N, Singh R, Madsen D, Lolans K, Lomovskaya O, Oza U, Dudley MN. Lemoine RC, et al. Among authors: lolans k. Bioorg Med Chem Lett. 2004 Oct 18;14(20):5127-31. doi: 10.1016/j.bmcl.2004.07.070. Bioorg Med Chem Lett. 2004. PMID: 15380213
Quinazolinone fungal efflux pump inhibitors. Part 3: (N-methyl)piperazine variants and pharmacokinetic optimization.
Watkins WJ, Chong L, Cho A, Hilgenkamp R, Ludwikow M, Garizi N, Iqbal N, Barnard J, Singh R, Madsen D, Lolans K, Lomovskaya O, Oza U, Kumaraswamy P, Blecken A, Bai S, Loury DJ, Griffith DC, Dudley MN. Watkins WJ, et al. Among authors: lolans k. Bioorg Med Chem Lett. 2007 May 15;17(10):2802-6. doi: 10.1016/j.bmcl.2007.02.047. Epub 2007 Feb 27. Bioorg Med Chem Lett. 2007. PMID: 17350259
CTX-M-12 beta-lactamase in a Klebsiella pneumoniae clinical isolate in Colombia.
Villegas MV, Correa A, Perez F, Zuluaga T, Radice M, Gutkind G, Casellas JM, Ayala J, Lolans K, Quinn JP; Colombian Nosocomial Resistance Study Group. Villegas MV, et al. Among authors: lolans k. Antimicrob Agents Chemother. 2004 Feb;48(2):629-31. doi: 10.1128/AAC.48.2.629-631.2004. Antimicrob Agents Chemother. 2004. PMID: 14742223 Free PMC article.
69 results