Wiessler M - Search Results

1

Human hepatic and renal microsomes, cytochromes P450 1A1/2, NADPH:cytochrome P450 reductase and prostaglandin H synthase mediate the formation of aristolochic acid-DNA adducts found in patients with urothelial cancer.

Stiborová M, Frei E, Hodek P, Wiessler M, Schmeiser HH. Stiborová M, et al. Among authors: wiessler m. Int J Cancer. 2005 Jan 10;113(2):189-97. doi: 10.1002/ijc.20564. Int J Cancer. 2005. PMID: 15386410

2

Carcinogenic aristolochic acids upon activation by DT-diaphorase form adducts found in DNA of patients with Chinese herbs nephropathy.

Stiborová M, Frei E, Sopko B, Wiessler M, Schmeiser HH. Stiborová M, et al. Among authors: wiessler m. Carcinogenesis. 2002 Apr;23(4):617-25. doi: 10.1093/carcin/23.4.617. Carcinogenesis. 2002. PMID: 11960915

3

Rat microsomes activating the anticancer drug ellipticine to species covalently binding to deoxyguanosine in DNA are a suitable model mimicking ellipticine bioactivation in humans.

Stiborová M, Stiborová-Rupertová M, Borek-Dohalská L, Wiessler M, Frei E. Stiborová M, et al. Among authors: wiessler m. Chem Res Toxicol. 2003 Jan;16(1):38-47. doi: 10.1021/tx0200818. Chem Res Toxicol. 2003. PMID: 12693029

4

Human cytosolic enzymes involved in the metabolic activation of carcinogenic aristolochic acid: evidence for reductive activation by human NAD(P)H:quinone oxidoreductase.

Stiborová M, Frei E, Sopko B, Sopková K, Marková V, Lanková M, Kumstýrová T, Wiessler M, Schmeiser HH. Stiborová M, et al. Among authors: wiessler m. Carcinogenesis. 2003 Oct;24(10):1695-703. doi: 10.1093/carcin/bgg119. Epub 2003 Jul 17. Carcinogenesis. 2003. PMID: 12869422

5

DNA adduct formation by the anticancer drug ellipticine in rats determined by 32P postlabeling.

Stiborová M, Breuer A, Aimová D, Stiborová-Rupertová M, Wiessler M, Frei E. Stiborová M, et al. Among authors: wiessler m. Int J Cancer. 2003 Dec 20;107(6):885-90. doi: 10.1002/ijc.11511. Int J Cancer. 2003. PMID: 14601046

6

The anticancer drug ellipticine forms covalent DNA adducts, mediated by human cytochromes P450, through metabolism to 13-hydroxyellipticine and ellipticine N2-oxide.

Stiborová M, Sejbal J, Borek-Dohalská L, Aimová D, Poljaková J, Forsterová K, Rupertová M, Wiesner J, Hudecek J, Wiessler M, Frei E. Stiborová M, et al. Among authors: wiessler m. Cancer Res. 2004 Nov 15;64(22):8374-80. doi: 10.1158/0008-5472.CAN-04-2202. Cancer Res. 2004. PMID: 15548707

7

Characterization of DNA adducts formed by aristolochic acids in the target organ (forestomach) of rats by 32P-postlabelling analysis using different chromatographic procedures.

Stiborová M, Fernando RC, Schmeiser HH, Frei E, Pfau W, Wiessler M. Stiborová M, et al. Among authors: wiessler m. Carcinogenesis. 1994 Jun;15(6):1187-92. doi: 10.1093/carcin/15.6.1187. Carcinogenesis. 1994. PMID: 8020154

8

Direct evidence for the formation of deoxyribonucleotide adducts from carcinogenic N-nitroso-N-methylaniline revealed by the 32P-postlabeling technique.

Stiborová M, Schmeiser HH, Wiessler M, Frei E. Stiborová M, et al. Among authors: wiessler m. Cancer Lett. 1999 Apr 26;138(1-2):61-6. doi: 10.1016/s0304-3835(98)00369-3. Cancer Lett. 1999. PMID: 10378774

9

Human enzymes involved in the metabolic activation of carcinogenic aristolochic acids: evidence for reductive activation by cytochromes P450 1A1 and 1A2.

Stiborová M, Frei E, Wiessler M, Schmeiser HH. Stiborová M, et al. Among authors: wiessler m. Chem Res Toxicol. 2001 Aug;14(8):1128-37. doi: 10.1021/tx010059z. Chem Res Toxicol. 2001. PMID: 11511187

10

Evidence for reductive activation of carcinogenic aristolochic acids by prostaglandin H synthase -- (32)P-postlabeling analysis of DNA adduct formation.

Stiborová M, Frei E, Breuer A, Wiessler M, Schmeiser HH. Stiborová M, et al. Among authors: wiessler m. Mutat Res. 2001 Jun 27;493(1-2):149-60. doi: 10.1016/s1383-5718(01)00171-1. Mutat Res. 2001. PMID: 11516724

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