Nikolovska-Coleska Z - Search Results

1

Breast cancer cells can evade apoptosis-mediated selective killing by a novel small molecule inhibitor of Bcl-2.

Real PJ, Cao Y, Wang R, Nikolovska-Coleska Z, Sanz-Ortiz J, Wang S, Fernandez-Luna JL. Real PJ, et al. Cancer Res. 2004 Nov 1;64(21):7947-53. doi: 10.1158/0008-5472.CAN-04-0945. Cancer Res. 2004. PMID: 15520201

2

Discovery of embelin as a cell-permeable, small-molecular weight inhibitor of XIAP through structure-based computational screening of a traditional herbal medicine three-dimensional structure database.

Nikolovska-Coleska Z, Xu L, Hu Z, Tomita Y, Li P, Roller PP, Wang R, Fang X, Guo R, Zhang M, Lippman ME, Yang D, Wang S. Nikolovska-Coleska Z, et al. J Med Chem. 2004 May 6;47(10):2430-40. doi: 10.1021/jm030420+. J Med Chem. 2004. PMID: 15115387

3

Structure-based design, synthesis, and evaluation of conformationally constrained mimetics of the second mitochondria-derived activator of caspase that target the X-linked inhibitor of apoptosis protein/caspase-9 interaction site.

Sun H, Nikolovska-Coleska Z, Yang CY, Xu L, Tomita Y, Krajewski K, Roller PP, Wang S. Sun H, et al. J Med Chem. 2004 Aug 12;47(17):4147-50. doi: 10.1021/jm0499108. J Med Chem. 2004. PMID: 15293984

4

Development and optimization of a binding assay for the XIAP BIR3 domain using fluorescence polarization.

Nikolovska-Coleska Z, Wang R, Fang X, Pan H, Tomita Y, Li P, Roller PP, Krajewski K, Saito NG, Stuckey JA, Wang S. Nikolovska-Coleska Z, et al. Anal Biochem. 2004 Sep 15;332(2):261-73. doi: 10.1016/j.ab.2004.05.055. Anal Biochem. 2004. PMID: 15325294

5

Structure-based design of spiro-oxindoles as potent, specific small-molecule inhibitors of the MDM2-p53 interaction.

Ding K, Lu Y, Nikolovska-Coleska Z, Wang G, Qiu S, Shangary S, Gao W, Qin D, Stuckey J, Krajewski K, Roller PP, Wang S. Ding K, et al. J Med Chem. 2006 Jun 15;49(12):3432-5. doi: 10.1021/jm051122a. J Med Chem. 2006. PMID: 16759082

6

Antiangiogenic effect of TW37, a small-molecule inhibitor of Bcl-2.

Zeitlin BD, Joo E, Dong Z, Warner K, Wang G, Nikolovska-Coleska Z, Wang S, Nör JE. Zeitlin BD, et al. Cancer Res. 2006 Sep 1;66(17):8698-706. doi: 10.1158/0008-5472.CAN-05-3691. Cancer Res. 2006. PMID: 16951185

7

Design, synthesis, and characterization of new embelin derivatives as potent inhibitors of X-linked inhibitor of apoptosis protein.

Chen J, Nikolovska-Coleska Z, Wang G, Qiu S, Wang S. Chen J, et al. Bioorg Med Chem Lett. 2006 Nov 15;16(22):5805-8. doi: 10.1016/j.bmcl.2006.08.072. Epub 2006 Sep 8. Bioorg Med Chem Lett. 2006. PMID: 16962773

8

Structure-based design of potent small-molecule inhibitors of anti-apoptotic Bcl-2 proteins.

Wang G, Nikolovska-Coleska Z, Yang CY, Wang R, Tang G, Guo J, Shangary S, Qiu S, Gao W, Yang D, Meagher J, Stuckey J, Krajewski K, Jiang S, Roller PP, Abaan HO, Tomita Y, Wang S. Wang G, et al. J Med Chem. 2006 Oct 19;49(21):6139-42. doi: 10.1021/jm060460o. J Med Chem. 2006. PMID: 17034116

9

A novel BH3 mimetic reveals a mitogen-activated protein kinase-dependent mechanism of melanoma cell death controlled by p53 and reactive oxygen species.

Verhaegen M, Bauer JA, Martín de la Vega C, Wang G, Wolter KG, Brenner JC, Nikolovska-Coleska Z, Bengtson A, Nair R, Elder JT, Van Brocklin M, Carey TE, Bradford CR, Wang S, Soengas MS. Verhaegen M, et al. Cancer Res. 2006 Dec 1;66(23):11348-59. doi: 10.1158/0008-5472.CAN-06-1748. Cancer Res. 2006. PMID: 17145881

10

Design, synthesis, and evaluation of a potent, cell-permeable, conformationally constrained second mitochondria derived activator of caspase (Smac) mimetic.

Sun H, Nikolovska-Coleska Z, Lu J, Qiu S, Yang CY, Gao W, Meagher J, Stuckey J, Wang S. Sun H, et al. J Med Chem. 2006 Dec 28;49(26):7916-20. doi: 10.1021/jm061108d. J Med Chem. 2006. PMID: 17181177

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